You searched for "xerostomia"

11 results found

Is submandibular gland transfer effective in prevention of post irradiation xerostomia in head and neck cancer patients?

Post irradiation xerostomia is a common side effect of irradiation to the head and neck region, with up to 90% of patients reporting some symptoms. Submandibular glands account for 70% of resting saliva production. Surgically transferring the submandibular gland to...

What is the quality of patient-reported outcomes of salivary function?

Salivary gland dysfunction has multiple causes and can have significant impact on quality of life, particularly when symptoms are severe. There are several patient-reported outcomes (PROMS) that assess these issues; however, these are variable in what they measure. This systematic...

Surgery for drooling

This paper looks at the surgical options for sialorrhoea once the first two options of behavioural and physiotherapy interventions and pharmacotherapy have been exhausted. The social impact of sialorrhoea on patients and their families is significant and often lifelong therefore...

Paediatric nasopharyngeal carcinoma

Between 11 and 18% of nasopharyngeal carcinomas (NPC) occur in the paediatric age group but there are no specific management guidelines for this age group. Tunisia is a region with an intermediate incidence of NPC, the authors studied 40 cases...

Identifying clinically useful salivary substitutes

This in vitro study analysed the efficacy of salivary substitutes used in the treatment of xerostomia following head neck irradiation. The researchers applied the products under evaluation onto a synthetic surface and onto cellular gingival models. The products were then...

Hyposalivation: a review of current and future treatments

Hyposalivation remains a stubbornly difficult condition to treat, but novel therapies may not be far away. Saliva has many essential functions, including aiding digestion and swallowing, lubrication, maintaining tooth integrity and antibacterial activity. When patients experience reduced saliva production (hyposalivation),...

Assessment and management of dysphagia in the elderly

This article covers dysphagia in older patients, which is an important topic due to an ageing population, and a relatively common symptom that we see in clinic. Dysphagia could be due to presbyphagia secondary to changes in head and neck...

Grading dysphagia as a toxicity in treating head and neck cancer

Common Terminology Criteria for Adverse Events (CTCAE) is a system used by clinicians to grade the toxicity of oncology treatments in a standardised manner. Dysphagia is perhaps the most common long-term toxicity of head and neck cancer treatment. Currently, a...

Medication and its effect on the larynx

This article summarises different medications and their effect on the voice. A growing number of patients we see in clinic are on multiple medications that could affect vocal cord function. The author summarises different classes of medications and their potential...

The astronomer’s nose: Tycho Brahe’s controversial prosthesis

Tycho Brahe (1546-1601) is a familiar and colourful figure in the history of science. The immense quantity of data he collected during his lifetime would enable the work of Johannes Kepler and has gained him admission to the astronomical pantheon....

Acoustic shock: definitions and clinical aspects

Acoustic shock, a previously little-known and poorly understood clinical entity, came to the public’s attention in 2019 due to a high-profile legal case of a musician at the Royal Opera House. In this fascinating article, Andrew Parker and William Parker...