You searched for "trial"
Sham controlled trial: BPPV
1 September 2014
| Andy Hall
I was drawn to this study and it proved an enlightening read; it also is a good example of where recommendations of a Cochrane review for long-term evidence of benefit have been acted upon! The study looked at the efficiency...
A trial of house dust mite sublingual tablet in children with allergic rhinitis
1 May 2019
| Shiying Hey
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ENTA - Audiology - Adult, ENTA - Auditory Implants, Neurotology, Otology, ENTA - Tinnitus, ENTA - Vestibular Disorders
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SIT, SLIT, allergens, inhalative allergens, rhinitis, allergic, clinical trials, specific immunotherapy
The house dust mite (HDM) is one of the commonest causative agents in allergic rhinitis (AR), affecting patients across all demographics. Recently, sublingual immunotherapy (SLIT) has been shown in clinical trials and meta-analysis to be effective compared to placebo in...
Controlled clinical trial results for FDA-approved tinnitus treatment device Lenire published in Nature Communications
12 September 2024
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Company Profiles, Research & Development
Nature Communications has published the peer-reviewed results of Neuromod Devices’ TENT-A3 (Treatment Evaluation of Neuromodulation for Tinnitus – Stage A3) clinical trial for the first and only FDA-approved bimodal tinnitus treatment device, Lenire.
Neuromod publishes results of second large-scale clinical trial for tinnitus, shows greater improvement of symptoms
7 July 2022
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Research & Development
Neuromod Devices, the medical device company specialising in tinnitus, has published the results of its TENT-A2 (Treatment Evaluation of Neuromodulation for Tinnitus – Stage A2) clinical trial in the scientific journal, Nature – Scientific Reports in a paper titled ‘Different bimodal neuromodulation settings reduce tinnitus symptoms in a large randomized trial’.
From a dysphagia clinical trial to a multidisciplinary head and neck clinical pathway – the road to implementation
1 May 2019
| Roganie Govender
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ENTA - Auditory Implants
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Clinical pathway, Deglutition, Deglutition disorders, Dysphagia, Head and neck cancer, Implementation, Nutrition, Oral intake
This paper describes the barriers and facilitators to establishing a structured and coordinated multidisciplinary care pathway for patients with head and neck cancer at a medical centre in the USA. The initiative was set in motion by the roll out...
Dupilumab prospective RCT for CRSwNP, a multinational trial of 60 patients with a 16-week CT follow-up
7 January 2021
| Suki Ahluwalia
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ENTA - Rhinology / Sinus
This transcontinental work describes a randomised, double blind, placebo controlled parallel group study over a 16-week period, assessing 60 patients with CRSwNP by CT scan scores. All patients had a four-week period of intranasal corticosteroids followed by randomisation to add...
New sites needed for STARFISH trial
26 February 2025
The STARFISH Trial is aiming to recruit 525 participants with sudden hearing loss from 75 ENT departments treating idiopathic sudden sensorineural hearing loss (ISSNHL).
Landmark clinical trial into treatment for severe hearing loss launches
3 January 2022
Researchers at the NIHR Nottingham Biomedical Research Centre and the University of Nottingham are launching a new study, sponsored by the University of Nottingham, which will inform the most effective treatment for people with severe hearing loss globally (those with...
OAEE UPDATE - Urgent Call for Surgical Supplies in Ukraine
24 March 2022
UK professionals have called for aid in sending surgical equipment to Ukraine during Russian invasion.
A place for everything and everything in its place: the practicalities of randomised clinical trials
1 November 2016
| Bonnie Millar
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ENTA - Audiology - Adult
Will this pill cure tinnitus? Bonnie Millar describes one trial that has investigated the possibility whilst describing the path of drug trials in the UK. Background In the last quarter of 2014, a clinical trial (QUIET-1; ClinicalTrials.gov Identifier: NCT02315508) commenced...
CRSwNP initiation, not always an interleukin fault
CRSwNP, similar to asthma, is an inflammatory disorder (type II) with eosinophilia and raised IL-5 and IL-13. Inflammation in CRSwNP is thought to be started by IL-25, IL-33 and thymic stromal lymphopoietin (TSLP), all of which form an important part...Gene therapy restores baby’s hearing
31 May 2024
The guest editor of a forthcoming supplement for ENT & Audiology News has helped enable a baby girl born deaf to hear unaided for the first time.
