You searched for "rhinosinusitis"
Fungal rhinosinusitis
Allergic fungal rhinosinusitis (AFRS) has been defined by the following characteristics: presence of nasal discharge, nasal obstruction, decreased sense of smell or facial pressure for 12 weeks, mucin within the sinus cavity containing fungal hyphae and degranulating eosinophils, endoscopic evidence...
Outcomes in rhinosinusitis
This review goes through the various different ways of assessing outcomes and describes the pros, cons and limitations of each. The different methods are described in the context of guidelines in diagnosis and management and compared with other conditions such...
Zinc and rhinosinusitis
Patients with chronic rhinosinusitis (CRS) in general, and those with nasal polyps (CRSwNP) in particular, have been shown to have down-regulation of tight junction genes. Zinc, on the other hand, is well-known for its role in immune regulation and deficiency...
A new biomarker for chronic rhinosinusitis
This Chinese study looked at the feasibility of periostin (usually found in bone and lung tissue) as a biomarker for chronic rhinosinusitis. They sampled ethmoid mucosa in 12 patients with chronic rhinosinusitis without nasal polyposis (CRSsNP) and 25 patients with...
Passive smoking and rhinosinusitis
One would expect that subjects exposed to more passive smoke would have a significantly increased level of rhinosinusitis. This study looked at a reasonable number of sinusitis and control subjects (404 and 165) using hair nicotine as an assessment of...
Chronic rhinosinusitis and sleep
This is an interesting article from the Chung Shan Medical University in Taiwan. One-hundred-and-thirty-nine patients were enrolled into this five-year study. They all had chronic rhinosinusitis with or without polyposis and underwent sinus surgery. The aim was to investigate a...
Antioxidants for bacterial rhinosinusitis
This Turkish laboratory animal-based study looked at the effects of alpha-lipoic acid on inflammation, oxidative status, and tissue integrity in an animal model of experimentally induced acute rhinosinusitis and to compare these effects with antibiotic treatment using cephalosporins. Alpha-lipoic acid...Targeting the microbiome in chronic rhinosinusitis
Researchers at St Paul’s Sinus Centre and UBC in Vancouver are testing a novel treatment for CRS: transferring mucus from a healthy donor into a patient’s sinuses. Chronic rhinosinusitis (CRS) is one of the most common diseases managed by otolaryngologists...
Standardising outcome measures in chronic rhinosinusitis
This international paper, involving the foremost rhinology departments worldwide aims to provide a standardised, agreed core outcome set for chronic rhinosinusitis, which has been designed to facilitate future meta analyses of published work in systematic reviews. Stakeholders included patients, ENT...
A review of topical treatments for chronic rhinosinusitis
Topical nasal treatment is considered the mainstay treatment for chronic rhinosinusitis (CRS). The authors reviewed the effectiveness of saline irrigation, topical corticosteroids, topical antibiotics and topical antifungals in the treatment of CRS. Large volume saline irrigation was found to be...
