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Intratympanic treatments for subjective idiopathic tinnitus

Direct application of medication into the ear is long established, going back as far as written records. In the modern era, greater understanding of aural anatomy revealed that drugs instilled in the middle ear could potentially diffuse into the cochlea...

Daflon – a new way to treat idiopathic epistaxis

Epistaxis is a common ENT emergency and most cases are idiopathic. Flavonoids are natural substances with variable phenolic structures that are found in fruit and vegetables and take effect on blood vessels. Daflon is proposed to control epistaxis by “improving...

The middle way: treating idiopathic facial nerve palsy

Whilst the causes of recurrent facial nerve palsy are numerous, in many cases it may be idiopathic. There is no clear consensus on treatment of this condition and conservative management alone may condemn patients to gradually worsening facial nerve function...

Paediatric idiopathic sudden sensorineural hearing loss

This Turkish retrospective study looked at the radiological and clinical characteristics, prognostic factors and treatment outcomes in children diagnosed with idiopathic sudden sensorineural hearing loss (ISSNHL). Forty-eight children were included over an eight-year period. Complete recovery (CR) was achieved in...

Idiopathic sudden sensorineural hearing loss and vertigo

This prospective longitudinal study evaluated vestibular function inpatients with idiopathic sudden sensorineural hearing loss (ISSHL) using caloric and video head impulse tests. All patients were admitted for treatment of their ISSHL and divided into two cohorts depending on presence or...

Neurological idiopathic disease: a shared journey for NASA and medicine

Whilst Southampton can’t really be described as an extreme environment, experiments carried out in the city have certainly been taken out of this world. Robert Marchbanks discusses one of the associations between Southampton, The International Space Station and tympanic membrane...

Leptin has no role in idiopathic sudden sensorineural hearing loss

This paper from Turkey claims to be the first study dealing with the relationship between leptin and idiopathic sudden sensorineural hearing loss (ISSHL). I remember leptin being a fashionable topic in obesity research, when leptin deficiency was thought to be...

Does stress and anxiety worsen idiopathic sudden hearing loss outcomes?

There have been suggestions that the natural course of the idiopathic sudden sensorineural hearing loss (ISSNHL) is not affected by intensive therapy. There is speculation as to whether unknown factors affect the treatment prognosis. This is a retrospective study of...

Prognostic value of vascular ultrasonographic findings in patients with idiopathic sudden sensorineural hearing loss

Sudden sensorineural hearing loss is often idiopathic. Although the aetiology of idiopathic sudden sensorineural hearing loss (ISSNHL) is unclear, vascular compromise is one of the frequently proposed hypotheses to explain its pathophysiology. Existing studies have shown an association between ISSNHL...

Transverse venous sinus stenosis – a risk factor for CSF leak in patients with idiopathic intracranial hypertension

This was a multicentre (six French tertiary hospitals) retrospective case-controlled study aiming to investigate the rate of transverse venous sinus stenosis (TVSS) in patients with idiopathic intracranial hypertension (IIH) with nasal cerebrospinal fluid (CSF) leaks. They compared the preoperative MRI...

Recovery rates in sudden sensorineural hearing loss

Sudden sensorineural hearing loss (SSNHL) is most commonly idiopathic, and is seen relatively frequently in ENT practice. Recovery spans a period of around 1-2 months, and ultimate outcomes are highly variable, from complete recovery to no detectable hearing. Although the...

Head injury and prolonged bed rest, but not inner ear disease, predict poorer outcome after Epley manoeuvre in posterior semicircular canal benign paroxysmal positional vertgo (P-BPPV)

This Japanese study included 197 patients with P-BPPV treated over a two and a half year period. The vast majority had idiopathic BPPV (n=157). The remaining 40 had secondary BPPV, eight following head trauma, 14 due to prolonged bed rest...