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Low risk options following failure of intratympanic gentamicin for Meniere’s

This article is a useful summary of the options available when intratympanic gentamicin (ITG) fails to adequately control vertigo episodes in Meniere’s patients. The authors describe the anatomical reasons that may impede drug delivery to the round window with the...

Does pre-op intratympanic gentamicin improve balance control after vestibular schwannoma surgery?

This retrospective study was based on data from 44 patients selected from a cohort of 153 who had undergone surgical resection of vestibular schwannoma over a 10-year period. The aim was to evaluate the dynamics of the postural control system...

N-acetylcysteine may have a role in the protection of cochlear hair cells

Gentamycin is an aminoglycoside antibiotic which is widely used throughout the world, despite its ototoxic potential. It therefore seems wise to continue the search for accessible otoprotective agents. The aim of this study was to clarify the potential protective role...

Review of surgical treatments of intractable Meniere’s disease

This is a nice summary of the evidence available for the surgical treatments for intractable Meniere’s disease. To summarise, in five-10 years, over 90% of vestibular neurectomy cases, more than 80% of intratympanic gentamycin treatment, and 70-80% of endolymphatic sac...

Office-based otology procedures

This edition of the Otolaryngologic Clinics of North America covers office-based surgery in ENT. This article discusses procedures in otology that could be performed in the outpatient setting and covers innovations in office-based otologic procedures. The endoscope features prominently in...

New aminoglycosides with reduced ototoxicity risk

Aminoglycoside antibiotics are widely used for infections affecting patients of all ages and at different sites, however they carry a risk of ototoxicity, nephrotoxicity and rarely peripheral neuropathy. Preventing ototoxicity is crucial to the maintenance of auditory function and quality...

Emerging antimicrobial resistance in ENT outpatients

Given the recent statement from the UK Prime Minister on this issue, it would appear timely to assess the ‘time bomb’ of antibiotic resistance in otology. Comparison of ear swabs over twelve months from 2007 and 2012 demonstrates an increasing...

Canal plugging for intractable Meniere’s disease

In this single centre retrospective study, the authors applied semicircular canal plugging, well known as a treatment for refractory BPPV, to intractable unilateral Meniere’s disease (MD) that had failed to respond to medical treatment with betahistine and hydrochlorothiazide. However, in...

Rapid genetic testing to avoid hearing loss in neonates

Thousands of newborn babies could avoid a lifetime of hearing loss thanks to a new rapid genetic test. In this article, we learn how. We have demonstrated for the first time that a rapid genetic test from a cheek swab...

Reviewing Meniere’s disease

This was a sizeable literature review (93 references) of not only the office-based treatments for Meniere’s disease but also the various aetiological theories regarding it. They also highlight the amended International Criteria for Meniere’s disease diagnosis (2015), comparing it against...

What do we put in our nasal douches? Anything?

The rise of the popularity of saline nasal douches, with several commercial preparations available, may be a rediscovery of an age-old tradition, but it has been shown to benefit patients. The question then arises as to whether this can be...

The modern management of Ménière's disease

In this article, John Phillips considers the evolution of management options for Ménière’s disease. Treatment options past and present are discussed, together with an insight into future developments regarding the role of intratympanic steroids. Ménière's disease can be the source...