You searched for "adenomas"

105 results found

Stereotactic radiosurgery for pituitary adenomas

Residual and recurrent functioning pituitary adenomas can be difficult to delineate on postoperative MRI scans, making them difficult targets for stereotactic radio surgery. In such cases radiation delivery to the entire sellar has been utilised as a radio surgical equivalent...

Rare, aggressive pituitary adenomas

This is a review article on published cases of the rare Crooke’s pituitary adenoma. These tumors are usually invasive and may be clinically aggressive; they may be endocrinologically silent or may produce adrenocorticotropic hormone causing Cushing’s disease. They often recur...

Paediatric versus adult pituitary adenomas

This retrospective study compares paediatric with adult patients undergoing pituitary adenoma surgery over a period of 26 years at a single institution. All surgeries were performed via a sublabial approach using the operating microscope. An endoscope was used occasionally for...

The increasingly favourable outcomes from endoscopic endonasal approaches for the management of pituitary adenomas

Historically, pituitary tumours have been surgically managed with an open, transcranial approach. Although this approach still has its merits in large intracranial adenomas, technological advancement has allowed smaller tumours to be debulked via a transseptal microscopic technique. These days, the...

Endoscopic transsphenoidal surgery versus dopamine agonist therapy for microprolactinomas

This study addresses the importance of the location of microprolactinomas in determining prognosis after surgery. Long-term dopamine agonist treatment is the current standard of treatment for microprolactinomas. However, patients often seek surgical removal. The authors of this study retrospectively analysed...

Review of pituitary tumour pathology

This is an excellent review article covering the pathology of pituitary adenomas (PA) as well as rare sellar lesions like lymphocytic hypophysitis that require aggressive treatment. The authors have preserved the 2017 World Health Organization (WHO) classification of PA and...

Finding the elusive parathyroid glands

While reading in the literature about new advances in knowledge and surgical techniques, it is often easy to lose track of the longstanding knowledge that we all acquired during our training. This is why this article on the anatomy and...

QoL post-endoscopic hypophysectomy

This prospective study conducted over four years surveyed more than 300 patients after endoscopic pituitary adenoma resection. The authors used the Anterior Skull Base Questionnaire-35 and the Sinonasal Outcome Test-22, and the scores were analysed for quality of life (QoL)...

Paediatric salivary gland tumours

This is a review article of a rare group of neoplasms that frequently present as painless preauricular mass in older children. There is a wide differential including first branchial arch abnormalities, inflammatory and granulomatous processes. Those masses that are painless,...

Malignant change of pleomorphic adenoma

Pleomorphic adenoma is the most common salivary gland tumour. The potential to undergo malignant transformation is rare but well described. The authors of this article present a case report of metastasis where the preceding submandibular gland pleomorphic adenoma preserves its...

Two for the price of one - multiple parotid neoplasms

With advancing years come many benefits, but one drawback is the acquisition of parotid (or thyroid) neoplasms. Conventional teaching is that most are benign and slowly enlarge, and not infrequently are found bilaterally as in Warthin’s. Pleomorphic adenomas are also...

Follicle stimulating hormone receptors; an aid for the pathologist?

It is well known that Follicle Stimulating Hormone receptors (FSHRs) are found in extra-gonadal tumours such as those within thyroid tissue. This Polish study analysed 44 thyroid resection specimens to look for the presence of these receptors. No mention is...