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The evidence for various treatments of autoimmune ear disease

The difficulty with this disease entity is that it is a heterogeneous group of conditions affecting the ear and a widely accepted diagnostic criteria does not exist. It is therefore difficult to conduct a well controlled trial and this systematic...

Intratympanic treatments for subjective idiopathic tinnitus

Direct application of medication into the ear is long established, going back as far as written records. In the modern era, greater understanding of aural anatomy revealed that drugs instilled in the middle ear could potentially diffuse into the cochlea...

Quo vadis FESS? Future directions in functional endoscopic sinus surgery

Endoscopic sinus surgery is now so ubiquitous that it is hard to imagine a time when it was not part of our clinical practice. Valentin Tomazic takes a look at its early development and looks ahead to endoscopic sinus surgery...

The integration of targeted therapy and surgery in advanced thyroid cancer clinical trials

One of the headline speakers, Mark Zafereo, will be talking at IFOS about thyroid cancer. We hear from his team about some of the areas they will be discussing. Locally advanced thyroid cancer generally refers to patients who have significant...

Is there a cause-and-effect relationship between allergic rhinitis and chronic rhinosinusitis?

This review examines the possible causative relationship between allergic rhinitis (AR) and chronic rhinosinusitis (CRS) that has long been proposed. Many observational and experimental studies exist, however no clear and definitive connection has been established. This is mainly due to...

People with dementia and their families want to see speech and language therapists!

Language and communication difficulties are common in Alzheimer’s disease and, of course, language-led dementia (primary progressive aphasia). Communication difficulties are highlighted as one of the biggest burdens for family members caring for loved ones with dementia. This is often associated...

Chorda tympani in middle ear surgery

This was a prospective study at a single Belgian centre that aimed to monitor postoperative taste problems after middle ear surgery. The authors also looked at the influence of pathology and manipulation of chorda tympani (CT) on its function. Taste...

Manual of Allergy and Clinical Immunology for Otolaryngologists

As a first approach, the book impresses with the hardback cover and the glossy 442 pages. Published in March 2015, the book reflects an effort to deliver the main advances and updates of allergy and clinical immunology relevant to otolaryngology...

A therapeutic algorithm for tracheoesophageal periprosthetic leakage

Tracheoesophageal voice prosthesis leakage can be intravalvular (more common) or periprosthetic (focus of this study). The authors studied the causes of periprosthetic leakage among 115 patients attending for voice prosthesis management (1374 clinic attendances) treated between December 2014 to December...

WCA Innovation Prize

At the World Congress of Audiology in Paris in September, a special prize was announced for the best innovation that addresses an unmet medical need. Candidates were selected from domains such as clinical trials or medical devices, and given five minutes and five slides to pitch in front of an international jury of researchers, clinicians, economists and industry professionals.

Auditory brainstem implant results in adults and children

Background The auditory brainstem implant (ABI) has been developed from cochlear implant (CI) technology and is indicated for people who have anatomical abnormalities of the cochlea or dysfunction of the auditory nerve. The majority of people who have received an...

A place for everything and everything in its place: the practicalities of randomised clinical trials

Will this pill cure tinnitus? Bonnie Millar describes one trial that has investigated the possibility whilst describing the path of drug trials in the UK. Background In the last quarter of 2014, a clinical trial (QUIET-1; ClinicalTrials.gov Identifier: NCT02315508) commenced...