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Recurrent ENT infections in children – is it a sign of primary immunodeficiency disease?

ENT clinicians often come across children with recurrent ear, sinus and pulmonary infections. These recurrent infections, albeit common in childhood, can represent an early sign of primary immunodeficiency diseases (PIDD). PIDD is an underdiagnosed group of genetic disorders involving absent...

Does stress and anxiety worsen idiopathic sudden hearing loss outcomes?

There have been suggestions that the natural course of the idiopathic sudden sensorineural hearing loss (ISSNHL) is not affected by intensive therapy. There is speculation as to whether unknown factors affect the treatment prognosis. This is a retrospective study of...

Predicting the prognosis of oral squamous cell carcinoma after salvage surgery

Loco-regional recurrence of oral cavity squamous cell carcinoma (OCSCC) continues to be a life-threatening and difficult clinical situation. Salvage surgery can result in significant morbidities, and survival following recurrence is generally poor. In this study from Ontario, Canada, prognostic factors...

Endonasal Endoscopic Surgery of Skull Base Tumors: An Interdisciplinary Approach

This book sets itself apart from its peers by providing a unique interdisciplinary approach to skull base surgery. As the title implies, there is naturally a huge focus on endoscopic endonasal skull base surgery (between chapters 8 and 15). The...

Predicting which oropharyngeal SCC HPV-positive patients should avoid de-escalated treatment

This study is timely for many reasons and raises very important questions in the management of the current rise in HPV-positive patients with oropharyngeal cancer (OPC). The uniqueness of this group within head and neck cancer in terms of favourable...

Long-term swallowing function in bilateral vocal cord immobility

Vocal cord immobility is the second most common abnormality of the larynx in the paediatric population. The team from New York aimed to characterise the long-term swallowing function in a cohort of patients with bilateral vocal cord immobility over a...

The video head impulse test: an aid to the diagnosis of spinocerebellar ataxias

Spinocerebellar and Friedreich ataxias (SCA and FA) by their nature present in neuro-otology clinics. The diagnosis is ultimately genetic but the authors investigated the characteristics of the VOR using the video head impulse test (vHIT) in order to distinguish between...

New MRI technique assesses treatment response in skull base osteomyelitis

This paper describes another useful imaging technique to monitor Necrotising Otitis Externa (NOE). Echoplanar diffusion weighted magnetic resonance (DW MR) shows high signal on the ‘ADC map’ with active disease and this reduces in signal intensity as symptoms improve. This...