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A drug to prevent hearing loss caused by ototoxic therapeutics
This editorial briefly highlights the progress made in discovering a compound named ORC-13661, which shows the potential to alter the response of hair cells to ototoxic medication. In the late 1980s, inner hair cells that were lost secondary to noise...
Do implants assist rehabilitation following mandibular reconstruction?
When undertaking mandibular reconstruction, optimal function and aesthetic rehabilitation is the goal. There is no doubt that patients consider chewing, swallowing and speech to be of paramount importance. Following surgery, suboptimal rehabilitation leads to a fall in quality of life...
REARRANGED: An Opera Singer’s Facial Cancer And Life Transposed
Rearranged is a wonderfully positive memoir telling of Kathleen Watt’s ordeal through maxillary osteosarcoma. As an early career opera singer in the New York Metropolitan Opera’s chorus, her dreams are derailed and life transformed when this most rare diagnosis hits....
Organoids in otolaryngology
This interesting review article summarises the status as well as future prospects of organoid technology in our field. Organoids are a mass of cells which are typically cultured in vitro with 3D technology. They simulate miniature tissues and organs and...
Vestibular schwannoma surgery and inner ear injuries
Iatrogenic inner ear injury during vestibular schwannoma (VS) surgery ranges between 20% and 30% in the literature. However, there is no up-to-date quantification of such injuries, hence this study. The authors conducted a US-multicentre database search looking for patients who...
Carotid paragangliomas and their management
Paragangliomas in the head and neck are most frequently associated with the carotid artery, classically at its bifurcation and splaying the internal and external vessels. Despite their commonality at this site, large studies of these rare tumours are still lacking...
MRI and the endolymphatic space
This is an interesting study which was performed to evaluate the endolymphatic space in patients with endolymphatic hydrops (EH), using MR imaging. Seven patients aged between 21–77 years; five female, two male with unilateral or bilateral symptoms of EH were...
Learning curve for sialendoscopy
Sialendoscopy represents a minimally invasive technique that permits direct salivary tree visualisation and treatment using endoscopic techniques. Previous studies have shown that it is an efficacious, safe and potentially gland preserving method to treat major salivary gland disease. However, it...
Auditory neuropathy spectrum disorder
This is a concise summary of auditory neuropathy and current knowledge of the disorder through review of a recently published article. The terminology of this hearing disorder implies the site of the lesion is neural; however the characteristic electrophysical signature...
The increasingly favourable outcomes from endoscopic endonasal approaches for the management of pituitary adenomas
Historically, pituitary tumours have been surgically managed with an open, transcranial approach. Although this approach still has its merits in large intracranial adenomas, technological advancement has allowed smaller tumours to be debulked via a transseptal microscopic technique. These days, the...
How should I excise sinonasal tumours, open or endoscopic? En bloc or piecemeal?
Sinonasal tumours often present late because initial symptoms mimic benign disease. They tend to produce more unilateral nasal symptoms, and patients with advance disease often describe paraesthesia and other cranial neuropathies. They only account for approximately 3% of upper aerodigestive...
