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Risk factors for loco regional recurrence for oral SCC
Over 250,000 cases of oral squamous cell carcinomas are diagnosed annually worldwide with 128,000 registered deaths. The authors of this study are from a single institution in Germany and have conducted a retrospective audit of 517 patients with oral SCC...
Preserving hearing in NF2 patients
Neurofibromatosis type 2 (NF2) is known to result in bilateral hearing loss, even when there is no significant tumour growth. The cause is postulated to be multifactorial: stretching and compression of the cochlear nerve by the tumour, impairment of labyrinthine...
Facial nerve grafting – what’s the wait?
An uninterrupted facial nerve after resection of cerebellopontine angle (CPA) tumour does not always translate into preserved facial animation. Fortunately there is a high probability spontaneous recovery may occur and hence patients are typically observed for 12 months postoperatively. However,...
Are elective facelifts a good idea after head and neck cancer radiotherapy?
The aim of this study was to assess the safety of elective cervicofacial rhytidectomy following radiotherapy for head and neck squamous cell carcinomas (HNSCC). A greater proportion of HNSCC patients are infected with certain strains of the human papillomavirus, which...
Lymph node ratio is a significant predictor for loco-regional recurrence after neck dissection in patients with papillary thyroid cancer
Lymph node metastases are common in papillary thyroid cancer (PTC), yet the impact of nodal metastases on survival remains unclear. Lymph node density (LND) is the ratio between the number of positive lymph nodes excised and the total number of...
No soup for you…! Early identification of postoperative perforation increases the success of conservative management
Iatrogenic perforation of the hypopharynx or cervical oesophagus is a well-recognised life-threatening complication. Previous studies have demonstrated that conservative management with broad-spectrum antibiotics and withholding oral feeding may avoid morbidity associated with surgical repair. This study addresses when conservative management...
Vestibular functions of hereditary hearing loss patients with GJB2 mutations
Mutations of the GJB2 gene are a common cause of deafness, being found in 15-25% of cases of congenital deafness. Over 100 mutations are now recognised and may be associated with a hearing loss ranging from mild to profound. This...
Speech audiometry tests in elderly patients with mild cognitive impairment
This paper caught my eye because, with our ageing population, mild cognitive impairment and dementia are a major, growing problem. We know that ageing causes a multitude of medical and social issues. So it seems wise to investigate the effects...
Three years later: report on the state of well-being of patients with chronic tinnitus who underwent modified tinnitus retraining therapy
This paper reports on 130 patients with tinnitus of at least three months duration who underwent ‘Modified Tinnitus Retraining Therapy’ (MTRT). MTRT combines psychological and physical therapies with standard tinnitus retraining therapy provided as a course of multi-disciplinary treatment, as...
Leptin has no role in idiopathic sudden sensorineural hearing loss
This paper from Turkey claims to be the first study dealing with the relationship between leptin and idiopathic sudden sensorineural hearing loss (ISSHL). I remember leptin being a fashionable topic in obesity research, when leptin deficiency was thought to be...
Association of sinonasal symptoms with ear disease
The study explores the possible association of sinonasal symptoms with ear disease. The subjects were patients with ear problems which were categorised as group A – patients with external ear problems (15%), group B1 – patients with middle ear mucosal...
