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Facial palsy: What do patients and healthcare care about?

The article describes the process for establishing a collaborative research agenda to address gaps in understanding of the diagnosis, treatment management of facial palsy. A Delphi technique was used in order to establish a facial palsy research agenda. In round...

Cochlear microphonics in children

Cochlear microphonics (CM) are generated mainly from outer hair cells and are routinely tested in children with hearing loss in some parts of the world. In this retrospective study, the aim was to compare the cochlear microphonics features (mainly CM...

Measuring is understanding: an unsupervised PROM clustering of CRS patients

It has been clear for quite some years, at least for anyone dealing daily with chronic rhinosinusitis (CRS) patients, that CRS is an ‘umbrella’ diagnosis. There are significant differences between patients, including different demographic data, different endoscopic and radiographic images,...

The role of macrolide antibiotics in chronic rhinosinusitis

The use of long-term antibiotics in the treatment of chronic rhinosinusitis is a contentious issue, not only because of the increasing problem with antibiotic resistance but also because of the potential cardiac risks, including sudden death. In this article, Anders...

ENT and evidence-based medicine: How do they benefit each other?

How do we assess evidence, and how should ENT surgeons use EBM? Evidence-based medicine (EBM) is the practice of medicine based upon high quality scientific research. There are several formal definitions of EBM, the most widely quoted being that of...

Facial Surgery: Plastic and Reconstructive

Following Professor Cheney’s first popular publication in 1995 on flaps and reconstruction and subsequent second edition, he has now co-edited with Tessa Hadlock a comprehensive two-volume production. They have put together an extensive range of plastic and reconstructive surgery in...

Hydrogen peroxide and its uses in healthcare

This is an interesting review about the origin and uses of hydrogen peroxide, especially in neurosurgery. However, its uses are ubiquitous and applicable to several medical specialties. When hydrogen peroxide was first discovered in 1818 by Louis Thenard, it had...

Are there any benefits of postoperative antibiotics after endoscopic transsphenoidal surgery for pituitary tumours?

This prospective randomised double-blind multicentre study evaluated whether postoperative antibiotics resulted in improvement in sinonasal quality of life (QoL) compared to placebo in patients undergoing endoscopic endonasal transsphenoidal pituitary surgery. A total of 461 patients were screened for the study...

The future of biologics?

This paper takes a deep dive into how eosinophilia affects the responsiveness of the host to the two monoclonal antibodies mepolizumab and bendralizumab, both of which are active against IL5. We know that eosinophils are attracted and trapped into the...

Early vs late activation of cochlear implant device

Device activation after cochlear implant surgery was typically performed after wound healing, and varies anytime from three to four weeks after surgery. Nowadays, activation is performed as early as two to three days after surgery. The authors evaluated the effect...

Postoperative pain in septoplasty

This is a prospective Turkish study that looked at factors affecting the postoperative pain response after septoplasty, a common ENT surgical procedure. Sixty patients were included in the study who underwent septoplasty. The authors looked at the influence of demographics...

Mind the gap – developing a sustainable pipeline for hearing therapeutics

In this article, the authors describe three key challenges faced in developing hearing therapeutics. Collaboration between companies, sectors and disciplines will be key to finding solutions. The unmet need for therapies for hearing loss grows apace, with prevalence rising across...