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The role of macrolide antibiotics in chronic rhinosinusitis

The use of long-term antibiotics in the treatment of chronic rhinosinusitis is a contentious issue, not only because of the increasing problem with antibiotic resistance but also because of the potential cardiac risks, including sudden death. In this article, Anders...

Robotic head and neck surgery: current state of the art and future innovations

Technology and innovation has provided modern head and neck surgeons with successive generations of robotic surgical systems, fibre-optic lasers, and novel tools which have ushered in a new era of minimally invasive surgery for tumours of the pharynx and larynx....

Role of potassium channel opener in salicylate induced tinnitus

The exact mechanism in the origin of tinnitus is not known. Many pharmacological agents have been tried to to treat tinnitus without great success. Aspirin is a commonly used medicine in the elderly population to reduce the risk of stroke...

Chronic cough hypersensitivity syndrome

We all have patients who give us a ‘heartsink’ feeling; for many of us, the coughing patient is exactly such a situation. In this overview, Bhaskar Ram and Sangeeta Maini outline their approach to diagnosis. Declan Costello, Editor. Introduction Chronic...

What’s new in protecting hearing?

Preventing an avoidable hearing loss before it begins would be the public health dream. In this article Kathleen Campbell takes us through one option that is showing the potential to fulfil that ambition. Kathleen explains the development of a preventative...

Targeting the microbiome in chronic rhinosinusitis

Researchers at St Paul’s Sinus Centre and UBC in Vancouver are testing a novel treatment for CRS: transferring mucus from a healthy donor into a patient’s sinuses. Chronic rhinosinusitis (CRS) is one of the most common diseases managed by otolaryngologists...

Robot controlled mastoid surgery!

This is a fascinating piece of work by a Korean team developing a human-robot collaborative control. Their model uses image guidance surgery to locate the drill tip’s position. Important structures can be highlighted – in this case the facial nerve....

A single blinded RCT comparing triamcinolone with 5-FU treatment for keloid scars

This single blinded RCT compared 43 patients with 50 symptomatic keloids that were randomised to two matched groups of 25 scars, receiving either 5-fluorouracil (5-FU) or current first line treatment, triamcinolone (TAC). The surgeon administering the injectable treatments was unblinded,...

Systemic agents in thyroid cancer

For those patients who have disseminated or unresectable thyroid cancer, Dr Arabella Hunt and Dr Kate Newbold review systemic treatments, their differences, toxicities and outcomes. Thyroid cancer is the most common endocrine malignancy. It is subdivided into differentiated (papillary, follicular...

Rosemary oil to aid surgical healing?

There are a multitude of ways in which to damage the nasal epithelium, whether iatrogenically through nasal surgery, via injury, allergy, infection or inhalation of an environmental pollutant. This study looks at the role of the herb rosemary, in the...

Cochlear implant referral: how can we do better?

Considerable progress has been made over the last few years in improving access to cochlear implantation (CI) in the UK for children and adults with severe to profound deafness. But we are still not treating children early enough, and we...

The changing landscape for hearing loss therapeutics: novel advances of gene and cell therapies

Recent years have seen advances in hearing loss therapeutics, with novel treatments trialled in humans, and others nearing promising first-in-kind clinical trials. First successful clinical trials for a specific form of genetic hearing loss Very exciting news has emerged in...