You searched for "therapeutics"
Role of sentinel lymph node biopsy in managing papillary thyroid cancer
Although studies have shown that the presence of lymph nodes metastases in papillary thyroid carcinoma does not alter survival, other studies have shown that it increases morbidity and mortality and that the presence of cervical lymph node metastasis at diagnosis...
OTO-104 in noise-induced and cisplatin-induced hearing loss
These two animal studies report on potential new applications for intra-tympanic OTO-104, a slow-release hydrogel formulation of dexamethasone that is currently being used in a Europe-wide randomised trial for Ménière’s disease. In the first paper, guinea pigs were given a...
Myringoplasty in a bottle?
Management of large traumatic TM perforations can involve observation and water precautions or surgical repair. Closure rates for larger perforations can be 8-12 weeks and occurs for between 38-79%. Animal and human studies have shown that exogenous application of epidermal...
Botulinum toxin injection for bilateral recurrent laryngeal nerve paralysis
All traditional surgical treatments for bilateral recurrent laryngeal nerve (RLN) paralysis are essentially a balance between maximising airway patency and ensuring adequate phonation / airway protection. This paper highlights the potential role of botulinum toxin (Botox) injection into the cricothyroid...
Role of potassium channel opener in salicylate induced tinnitus
The exact mechanism in the origin of tinnitus is not known. Many pharmacological agents have been tried to to treat tinnitus without great success. Aspirin is a commonly used medicine in the elderly population to reduce the risk of stroke...COOL therapy for cisplatin-induced hearing loss
Cisplatin is a commonly used cancer therapy, with nearly 50% of patients undergoing chemotherapy receiving cisplatin as part of their regimen [1]. Depending on the dose, incidence of hearing loss has been reported as 12-100% in adults, and 37-94% in...BLA announces membership election results
The British Laryngological Association (BLA) has announced the results of its bi-annual election.Psychogenic vestibular disorders: understanding and management
‘Psychogenic vestibular disorders’, also known as ‘functional vertigo and dizziness’, are common causes of dizziness and balance difficulty. Although our understanding of their underlying pathophysiology remains incomplete, Drs Diego Kaski and Amy Edwards outline how early identification and positive diagnosis...Developing outcome measures for research
There are challenges in developing outcomes measures; Professor Hall presents five top pointers for making rapid progress in developing outcome measures for research purposes. Anyone who has worked clinically with hearing loss will appreciate that every patient’s experience is personal....The future of rhinology: What will come first, a radical change in rhinological management or the decimation of the world?
In this article, Simon Gane looks forward to what the future holds, on the presumption he survives. Setting aside the questions of the UK even existing, the NHS still working, or the fact we’ll be commuting to our jobs in...
Doing it for the people: how to do speech and language therapy
This review article distils 58 studies, collating information from people with aphasia, their families and clinical speech and language therapists summarising the seven habits of highly effective aphasia therapists. Habit 1: Effective therapists invest time in and prioritise relationships with...
