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Predicting which oropharyngeal SCC HPV-positive patients should avoid de-escalated treatment
This study is timely for many reasons and raises very important questions in the management of the current rise in HPV-positive patients with oropharyngeal cancer (OPC). The uniqueness of this group within head and neck cancer in terms of favourable...Prednisolone and/or acyclovir for Bell’s palsy
Landmark Paper: Sullivan FM, Swan IRC, Donnan PT, et al. Early treatment with prednisolone or acyclovir in Bell’s Palsy. N Engl J Med 2007;357(16):1598-607. Facial nerve paralysis as a consequence of Bell’s palsy can result in devastating long-term effects on...
Clinicopathological features of follicular variant of papillary thyroid carcinoma
The follicular variant (FV) of papillary thyroid carcinoma (PTC) is characterised by the presence of nuclear features of PTC together with a follicular growth pattern. It is currently reported to make up 11.8% to 53.3% of all PTC cases. It...
Gastrostomy tube dependence following TORS
Transoral robotic surgery (TORS) for oropharyngeal squamous cell carcinoma (OPSCC) is now a well-established treatment modality for early (T1-T2) disease. Accumulating evidence suggests that one of its main benefits relative to conventional chemoradiotherapy is superior long-term functional outcome, especially with...
Prediction of morbidity and mortality in patients undergoing thyroid or parathyroid surgery
Major postoperative adverse events in thyroid or parathyroid surgery are uncommon. Various authors have developed risk indices to identify physical deficits in patients undergoing elective surgery. The literature is less clear about patients undergoing thyroid or parathyroid surgery. In this...
Incidental thyroid nodules: should we observe or operate?
Thyroid nodules are extraordinarily prevalent, detected by physical examination in 7% and by imaging studies in 67% of the population. Although most of these nodules are benign, up to 20% are found to be malignant on excision. It’s a very...
Lymph node metastases in papillary thyroid cancer
This retrospective Korean cohort study looked at the risk factors associated with bilateral lateral lymph node metastases in patients with unilateral papillary thyroid cancer. There were 11 patients who met the inclusion criteria across an 11-year period from 2009 to...
Chronic rhinosinusitis – a pre-malignant condition?
Nasopharyngeal carcinoma (NPC) is a relatively uncommon diagnosis in the West but is prevalent in Southeast Asia. Several factors have been established to be associated with a higher risk of developing NPC, including salted fish consumption, smoking, alcohol, and Epstein...
Can prediction models help identify dysphagia in ventilated patients?
Dysphagia commonly affects patients in intensive care units (ICU), particularly those on mechanical ventilation, and is associated with high risk of mortality. This systematic review and meta-analysis aimed to identify predictors for dysphagia in ventilated ICU patients by summarising existing...ERS Epistaxis
Topics: Risk factors and assessment - by Urban Geisthoff (15 mins) Stepwise treatment options - by Gwijde Andriaensen (15 mins) When that fails: surgery / embolisation - by Thibault van Zele (15 mins) Moderator - Sean Carrie, ERS PresidentCo-Host -...
Do anticoagulanis and facial plastic surgery mix?
Some surgeons think that antiplatelet and anticoagulant therapies (aspirin, warfarin sodium and clopidogrel bisulphate) increase perioperative bleeding and infections. However, the current evidence base provides conflicting data with respect to the risk of true complications. In this case-control study a...
