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The changing landscape for hearing loss therapeutics: novel advances of gene and cell therapies
Recent years have seen advances in hearing loss therapeutics, with novel treatments trialled in humans, and others nearing promising first-in-kind clinical trials. First successful clinical trials for a specific form of genetic hearing loss Very exciting news has emerged in...Staphylococcus aureus as a cause of refractory chronic rhinosinusitis
Staphylococcus aureus has long been linked to chronic rhinosinusitis, particularly recalcitrant cases. In this article, Alkis Psaltis describes how newer techniques have shown higher rates of S. aureus infection than were previously thought, and explains how the bacteria are able...The sound of music for adult cochlear implant recipients
Dr Valerie Looi has dedicated her academic career to investigating music perception in people who have cochlear implants, and more recently, the potential of music training for improving their music perception. This article outlines current research relating to music perception...Monitored safe medical practice: minimising patient harm will reduce medical negligence bill for the NHS
Patrick Bradley ruminates on a celebrated career in ENT head and neck surgery and suggests that increasing the possibility of positive outcomes to contemporary patient safety initiatives by the NHS must involve efforts to develop an enthusiastic contented workforce willing...
IV dexamethasone versus LA infiltration during paediatric tonsillectomy
Postoperative nausea and vomiting following tonsillectomy is important to control for improved oral intake and satisfaction following surgery. Optimal management is still debated. This team from Beirut conducted a randomised double blind clinical trial comparing the effect of intravenous dexamethasone...
Cervicogenic vertigo, a view from the experts
Many readers would be familiar with the term ‘cervicogenic vertigo’ to mean neck-related vertigo or dizziness. In simple terms, this disorder has been defined as dizziness/vertigo caused by neck pain and/or stiffness. By implication, the vertigo/dizziness should resolve by treating...ENT bodies stand up for Ukraine
Leading ENT and audiology organisations have made a stand against Russia’s war in Ukraine.
Help or hinder: how and why do SLTs make clinical decisions around swallowing?
Dysphagia is a relatively common consequence of stroke, with estimates between 50% and 60% of people presenting with swallowing dysfunction following stroke. It is associated with pneumonia, malnutrition and dehydration which in turn lead to increased length of hospital admission,...
Does stress and anxiety worsen idiopathic sudden hearing loss outcomes?
There have been suggestions that the natural course of the idiopathic sudden sensorineural hearing loss (ISSNHL) is not affected by intensive therapy. There is speculation as to whether unknown factors affect the treatment prognosis. This is a retrospective study of...
More markers for sinonasal diseases
In this study, nasal mucus cystatin SN levels were compared in patients with controlled and uncontrolled chronic rhinosinusitis (CRS). Cystatin SN is an epithelium-derived cytokine which regulates cysteine proteases and enhances IL-5 mediated activation of eosinophils. The study included 98...
Septoplasty under local and general anaesthetic
This Turkish prospective, non-randomised study compared the quality of life outcomes in 50 patients who underwent local anaesthetic (LA) septoplasty, and 50 patients who underwent general anaesthetic (GA) septoplasty over a six-month period. Quality of life outcomes were measured using...
