You searched for "genes"
Those little friends in our noses
Human microbiota plays an important role in both health and disease including metabolism, immunomodulation, and a potential role in chronic inflammatory conditions such as chronic rhinosinusitis (CRS). The authors aimed to investigate the sinonasal microbiome using 16S rRNA gene sequencing...
Age and sleep disorders as risk factors for Ménière’s disease
Decades after it was first described, the pathophysiology of Ménière’s disease is still a subject for research and discussion, with several controversies regarding its management. Several factors have been reported to cause Ménière’s disease including viral infections, allergies, genetic factors,...
Vestibular functions of hereditary hearing loss patients with GJB2 mutations
Mutations of the GJB2 gene are a common cause of deafness, being found in 15-25% of cases of congenital deafness. Over 100 mutations are now recognised and may be associated with a hearing loss ranging from mild to profound. This...4th Annual Inner Ear Disorders Therapeutics Summit
2024 has been an important year with recent back-to-back positive results for gene therapy for rare genetic hearing disorders and major headways in otoprotective, restorative and regenerative small molecules and cell therapies for acquired hearing loss. The Inner Ear Disorders...
Otolaryngology - Head and Neck Surgery: Rapid Clinical and Board Review
This is a book written by a group of ENT surgeons from the Mayo Clinic, and a plastic surgeon from Colorado, and is aimed at US residents throughout their training, in particular in preparation for their board exams. As such,...
Paediatric hearing following chemotherapy
This study examined the effect of platinum compounds on hearing in 104 children with solid tumours. As would be expected, this group was heterogeneous and included a range of ages, tumour types, chemotherapeutic agents and dosing regimens. Age-appropriate audiometry was...Vicarious (nasal) menstruation
Hippocrates himself is known to have said that when a woman’s menses are due, but instead of the usual vaginal menstrual flow, she has a haemorrhage from the nose, then this is a sure sign of pregnancy [1]. Artist’s impression...
