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Cancer genetics and signalling pathways in ENT – a review and discussion of how this can be applied to rare tumours
Introduction Cancer cases continue to increase worldwide, and head and neck cancer is a major global health issue, with an estimated global burden of over 630,000 new cases and over 350,000 deaths per year [1]. The term ‘head and neck...International Federation of Head and Neck Oncologic Societies (IFHNOS): its programmes and impact on head and neck cancer worldwide
In the first article of this edition, we introduce IFHNOS, which has created a major impact on the landscape of head and neck cancer treatment and education over the past quarter of a century by offering a global platform amongst...
Is submandibular gland transfer effective in prevention of post irradiation xerostomia in head and neck cancer patients?
Post irradiation xerostomia is a common side effect of irradiation to the head and neck region, with up to 90% of patients reporting some symptoms. Submandibular glands account for 70% of resting saliva production. Surgically transferring the submandibular gland to...
An algorithm to distinguish between distant metastases and metachronous lung primary in patients with HPV-related oropharyngeal cancer
Distinguishing between distant metastases of HPV-related oropharyngeal squamous cell carcinoma (OPSCC) and metachronous primary lung squamous cell carcinoma (SCC) is important as it has implications for treatment, prognosis counselling, and registry data. Although p16 immunohistochemistry (p16 IHC) is widely accepted...
Modifying two-week wait protocol for suspected head and neck cancer patients during COVID-19
As healthcare workers, we are committed to ensuring that our patients continue to receive the optimum care that we are set up to deliver. However, the last year has shown that we need to be mindful of balancing this with...
Can we predict risk of adverse events preoperatively in patients undergoing head and neck cancer surgery?
Ed’s Choice reviews a paper aiming to create a reliable index to predict postoperative outcomes in head and neck cancer patients. This interesting study identifies variables that may assist in risk assessing prospective surgical candidates. There have been a few...
Less pain more gain: impact of prophylactic gabapentin on swallowing outcomes in head and neck cancer patients undergoing radiation treatment
Patients planned for chemoradiation to the head and neck are usually advised to expect some pain and soreness during their treatment and that pain relief will be offered as and when it is required. Uncontrolled pain and mucositis affect oral...
Does transoral robotic surgery improve outcomes among patients with head and neck cancer of unknown primary?
A tonsillectomy and tongue base mucosectomy is becoming increasingly accepted as the optimal surgical intervention to aid in identifying the primary source of a p16+ / HPV-related squamous cell carcinoma (SCC) of unknown origin, given that this disease almost exclusively...
How do objective ratings of swallowing compare with patient-reported dysphagia QOL measures in the head and neck cancer population?
Swallowing may be assessed by a comprehensive battery of tools including instrumental/objective assessments, clinician-rated measures and patient-reported measures. The authors of this paper use secondary analysis to explore concordance between videofluoroscopy and a patient-reported dysphagia quality of life (QOL) measure....
KTP laser ablation for early glottic cancer
TLM for glottic carcinoma has historically been performed with a carbon dioxide (CO2) laser. A much smaller literature base has examined the use of potassium titanyl phosphate (KTP) laser in this context. This retrospective chart review aims to fill that...
T1 lip cancer and cervical lymph node metastases
The management of large lip squamous cell carcinoma (SCC) (T2, T3, T4 tumours) or those with nodal disease is well established. However the management of T1N0 tumours is controversial due to the assumed low risk of occult lymph node metastases....
