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The future of biologics?
This paper takes a deep dive into how eosinophilia affects the responsiveness of the host to the two monoclonal antibodies mepolizumab and bendralizumab, both of which are active against IL5. We know that eosinophils are attracted and trapped into the...
Allergen specific subcutaneous immunotherapy helps in prolonged control of allergic rhinitis
One of the commonest allergens involved in perennial allergic rhinitis is house dust mite. A good proportion of these cases prove intractable to treatment with oral and intranasal antihistamines and intranasal steroid sprays. Immunotherapy is considered a useful alternative and...
The stubborn polyp cases are ‘different’
The widely different behaviour of nasal polyp disease between patients is a major feature of rhinology practice and makes counselling of patients difficult when approaching their first operative intervention. Setting aside aspirin sensitivity (Samter’s triad), which is known to be...Diabetes and hearing loss: a review
As hearing health professionals we often ask, especially in older patients, if they have diabetes; but what is the link? How is it manifested and should it change current practice? Alec Lapira reviews the changing evidence. Early attempts to establish...Welcome to the new ENT UK President
We were delighted to participate in the ENT UK Spring Meeting on 15 April, which took place on ENT & Audiology News’ very own doorstep in the picturesque city of Edinburgh. Held in the Surgeon’s Quarter in the heart of...
The initial management of nasal trauma
Fractures of the nose are the most common facial fractures and reported to be the third most common fracture of the human skeleton. Nasal trauma can lead to obvious or more subtle loss of function or form and cosmetic compromise....A binaural detection task that reveals deficits in listeners having ‘slight’ or ‘hidden’ hearing loss
The association of degraded binaural processing in adults with clinically defined ‘slight’ or ‘hidden’ high frequency hearing loss is of great interest to clinicians if it can be measured. Leslie R Bernstein and Constantine Trahiotis share their findings in measurements...In conversation with Professor Janet Wilson
As she approaches her retirement from clinical practice, Professor Janet Wilson speaks to our Editor (and fellow laryngologist) Declan Costello about surgical training, research, diversity, literature and the future. You have had an immensely successful career in ENT – how...
Moderating effect of hearing aids on association between hearing loss and brain structure?
Previous studies have suggested links between age-related hearing loss and structural changes in cortical regions with auditory and language functions, which could be causative of cognitive decline linked to the condition. The authors reason reduced sensory input could be causative...
Is there an association with cognitive impairment and hearing loss in a developing country?
Hearing loss (HL) is the third leading chronic health condition among older adults. Most studies investigating HL and cognition have been performed in high-income countries. Risk factors for dementia (eg. hypertension, midlife hearing loss, obesity and physical inactivity) are more...
Recurrent facial palsy
Recurrent facial palsy is relatively rare, and its clinical features are not well known. The authors set out to investigate this further by undertaking a retrospective study of patients with recurrent facial palsy over a 14-year period. Only Bell’s palsy...
