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The changing landscape for hearing loss therapeutics: novel advances of gene and cell therapies

Recent years have seen advances in hearing loss therapeutics, with novel treatments trialled in humans, and others nearing promising first-in-kind clinical trials. First successful clinical trials for a specific form of genetic hearing loss Very exciting news has emerged in...

The evolution and advancements in radiological imaging of the sinuses

Computed tomography (CT) imaging is crucial in the planning of any endoscopic sinus operation; we hear from one of the pioneers of CT scanning who worked with Stammberger and Messerklinger in developing many of the technologies that we now take...

Quo vadis FESS? Future directions in functional endoscopic sinus surgery

Endoscopic sinus surgery is now so ubiquitous that it is hard to imagine a time when it was not part of our clinical practice. Valentin Tomazic takes a look at its early development and looks ahead to endoscopic sinus surgery...

The ear-brain connection in cochlear implant users: learning to listen again

While the cochlear implant (CI) has been a tremendous success in restoring hearing to deaf individuals, the implantation outcome still varies across CI users [1]. Some demographic factors, such as duration of deafness, and peripheral factors, such as electrode placement,...

Could social isolation be a factor in the link between hearing loss and dementia?

In 1802, Beethoven wrote to his brothers Carl and Johann about his hearing loss: “You men who think or say that I am malevolent, stubborn, or misanthropic, how greatly do you wrong me. You do not know the secret cause...

The power of the multidisciplinary team in paediatric cochlear implant assessment

Marette, Kate and Justine from the Birmingham Paediatric Centre give a detailed insight into how their team works together to assess children and young people for potential cochlear implantation. Cochlear implants and the specialist MDT The multidisciplinary team in cochlear...

Health related quality of life measures as outcome parameters in middle ear diseases

Surely the only outcome needed for post-surgical ears is a better PTA? Marcus Neudert argues there should be more to it than that. To draw a comprehensive picture of the disease-associated restrictions in patients with chronic otitis media, audiometric outcome...

What does functional neuroimaging tell us about tinnitus?

One of the most common causes of tinnitus is noise exposure, be that either cumulative day-to-day exposure over a lifetime or experience of acute noise trauma such as a loud concert or shooting incident. Observational data indicate that up to...