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Precision and personalised genomic and epigenomic medicine in audiology/hearing loss
A detailed look at the pathogenesis of acquired hearing loss due to exposure to ototoxicity during pregnancy or shortly after birth. Insights from genomic medicine have shown that, along with environmental factors causing epigenetic alterations, hearing loss may be caused...Congenital CMV: investigations and management in the audiology setting
Congenital cytomegalovirus (cCMV) is the only cause of congenital sensorineural hearing loss (SNHL) for which there is a medical treatment available to prevent further hearing loss. Dr Simone Walter discusses cCMV infection, cCMV-related hearing loss, and how to facilitate their...Doctors urged to treat patients with sudden hearing loss within seven days
A team of clinician scientists have identified the factors that predict full hearing recovery, with the strongest predictor being treatment with steroids within seven days of a sudden drop in hearing.
Can we predict risk of adverse events preoperatively in patients undergoing head and neck cancer surgery?
Ed’s Choice reviews a paper aiming to create a reliable index to predict postoperative outcomes in head and neck cancer patients. This interesting study identifies variables that may assist in risk assessing prospective surgical candidates. There have been a few...
Polysolmnography and laryngomalacia severity
Laryngomalacia represents the single most common cause of stridor in infants. Most cases are self-resolving, but a proportion of children will require surgical intervention. This group aimed to analyse the efficacy of polysomnography in determining the severity of laryngomalacia in...
Hearing aids in children for language development
This article summarises the current evidence and a recent study examining the factors influencing language development in children fitted with hearing aids in order to aid clinical decision making. The aims were to examine amplification factors that could be targeted...
Clinical assessment in OSA
This paper divides the assessment up into anatomical (nasal and oropharyngeal), endoscopic and imaging. It points out the salient features to look out for in OSA patients with regards the nasal valve and also oropharyngeal anatomy, with tonsil hypertrophy grading...
Treatment algorithm for olfactory disorders
The purpose of this paper is to review the current evidence in diagnosing olfactory disorders and suggest an algorithmic approach to patients with relevant complaints. Age-associated olfactory loss is often multifactorial and requires a careful history and physical exam. A...
‘Dead ear’ after mastoid surgery
The primary aim of surgery in the management of cholesteatoma is eradication of the disease which can potentially result in serious complications such as intracranial extension, facial nerve weakness and further hearing loss. A profound hearing loss resulting postoperatively considerably...
Food impaction in children is associated with eosinophilic oesophagitis
There is an increasing amount of evidence to suggest that chronic oesophageal inflammation and motility disorders play a more significant role in oesophageal food impaction (EFI) in children compared to structural defects. The authors conducted a retrospective study of children...
Sinonasal inverting papilloma: who is at risk of recurrence?
This study from a tertiary sinus surgery unit, describes some useful information in the follow-up of sinonasal inverted papilloma patients - in particular those likely to recur - and discusses the optimal staging systems to use to attempt to predict...
