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Hyposalivation: a review of current and future treatments

Hyposalivation remains a stubbornly difficult condition to treat, but novel therapies may not be far away. Saliva has many essential functions, including aiding digestion and swallowing, lubrication, maintaining tooth integrity and antibacterial activity. When patients experience reduced saliva production (hyposalivation),...

The changing spectrum of cancer of the oropharynx: dilemmas and future directions

The association of HPV in oropharyngeal cancer has identified a ‘new disease’, with its unique biologic behaviour, and challenges for clinicians in selecting therapeutic combinations offering maximum efficacy and minimum morbidity or long-term sequela currently under study in clinical trials....

In Memory: An Interview with Professor Leslie Michaels

The Memorial Service for Professor Leslie Michaels takes place next week (mid-April 2019). Professor Michaels was the former Professor of Pathology at the Institute of Laryngology and Otology at UCL and The RNTN&E Hospital. His inspirational achievements are worthy of...

Genetic discovery using animal models: presbyacusis

By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...

In conversation with George Tavartkiladze

For decades, Professor Tavartkiladze has been the personification of Russian audiology and its best known ambassador on the international stage. Hailing from the republic of Georgia, he has led countless seminal initiatives within Russia to advance the science and practice...

What’s happened since the European position paper on nose and sinus tumours?

The management of malignant sinonasal tumours has gone through radical changes in recent years. Prof Valerie Lund gives us an update based on her upcoming talk at IFOS. In 2010 when we published the European position paper on ‘endoscopic management...

Laryngology: past, present and future

Two laryngological authorities trace the history of laryngology, from ancient Rome to the modern day. The structure of the vocal folds was a matter of conjecture until the renaissance when anatomists such as Andreas Vesalius and Julius Casserius demonstrated the...

The future of rhinology: What will come first, a radical change in rhinological management or the decimation of the world?

In this article, Simon Gane looks forward to what the future holds, on the presumption he survives. Setting aside the questions of the UK even existing, the NHS still working, or the fact we’ll be commuting to our jobs in...

Tonsillitis and tonsillectomies: where do we go from Paradise?

Landmark Paper: Paradise JL, Bluestone CD, Bachman RZ, et al. Efficacy of tonsillectomy for recurrent throat infection in severely affected children – results of parallel randomized and nonrandomized clinical trials. N Engl J Med 1984;310(11):674-83. The Paradise paper on tonsillectomy...

In this issue...Inner Ear Therapeutics

Emma Stapleton, MBChB, FRCS (ORL-HNS), Consultant Otolaryngologist, Cochlear Implant and Skull Base Surgeon, Manchester Royal Infirmary, UK. E: emmastapleton@doctors.org.ukTwitter: @otolaryngolofox Ralph Holme, Director of Research and Insight, RNID, UK. Ralph. E: Holme@rnid.org.uk W: www.rnid.org.uk For Mar/Apr 2022, we sang the...

Detecting postoperative cholesteatoma with diffusion weighted magnetic resonance imaging

Middle ear cleft cholesteatoma is an inflammatory disease that erodes local bony structures and can cause otorrhea, hearing loss, vertigo and intracranial complications. It is usually treated with surgery, typically canal wall up (CWU) or canal wall down (CWD) surgery....

Loss of smell after COVID-19: a view from the patient forums

Patient advocate, Chrissi Kelly, founder of AbScent, talks about how the pandemic has changed the way we think about smell loss. The high prevalence of chemosensory impairment as a result of the SARS-CoV-2 virus has shone a much-needed spotlight on...