You searched for "malignant"

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Bile acids and pharyngeal malignancy

Laryngopharyngeal reflux is a commonly described condition. There is strong evidence linking gastro-oesophageal reflux with oesophageal carcinomas. Gastric refluxate consists of gastric acid, pepsin and bile acids. The roles of pepsin and acidic conditions in the development of laryngopharyngeal carcinoma...

Follicle stimulating hormone receptors; an aid for the pathologist?

It is well known that Follicle Stimulating Hormone receptors (FSHRs) are found in extra-gonadal tumours such as those within thyroid tissue. This Polish study analysed 44 thyroid resection specimens to look for the presence of these receptors. No mention is...

Head and neck cancer and PET-CT

Positron emission tomography-computed tomography (PET-CT) is an imaging technique in which abnormalities of tissue metabolism are precisely superimposed onto the anatomy. It relies on the premise that malignant cells are more metabolically active compared with non-malignant cells. On this basis,...

Detecting cancer margins during robotic head and neck cancer surgery using ambient mass spectrometry

We have known about altered metabolism in cancer cells since Otto Warburg described it 97 years ago. But can we take advantage of this knowledge in curing cancer? Jim Higginson explains the value of smoke generated during cancer surgery. The...

Medical and surgical management of performing vocalists

Dr Steven Zeitels is widely recognised as the foremost laryngologist of his generation. He has been at the forefront of innovation for 25 years, and has treated innumerable high-profile singers, most recently Sam Smith and Adele. Here, he gives us...

Complications in Otolaryngology – Head and Neck Surgery, First Edition

This is a volume compiled into a ‘handy reading’ format on Complications in Otolaryngology – Head and Neck Surgery, which cites as its special features: 1) the first complete, one-volume source on risks and complications in otology, rhinology, and head...

The newest robot from da Vinci – what can it offer for hypopharyngeal cancer surgery?

The standard existing da Vinci surgical robot (the Si model) has been much maligned for not being optimally designed for transoral access and endoscopic manoeuvrability in head and neck surgery. This preclinical work from Holsinger and his team looks at...

Complication rates for grommet insertion in H&N cancer patients

Otitis Media (OM) can be the direct result of H&N malignancy itself or secondary to treatment of malignancy. Both surgery and radiotherapy can cause lasting changes to the physiologic function of the ET, middle ear, tympanic membrane and ear canal....

Transnasal oesophagoscopy in head and neck cancer: an update

The role of transnasal oesophagoscopy (TNE) in the management of head and neck cancer patients is evolving. Until 1990, oesphagoscopy required specialist endoscopists, general anaesthesia or sedation. This review succinctly summarises updates in the evidence for TNE in: i) Screening...

Role of fine needle aspiration cytology in the management of thyroid neoplasm

Fine needle aspiration cytology (FNAC) is a useful procedure in the assessment of thyroid swellings. This retrospective study was done at King Abdul-Aziz University hospital, King Saud University, Riyadh. The objectives of this study were: to determine the cytological pattern...

Effects of air pollution and climate change on the upper airways

Dr Alexander Simidchiev is a specialist in internal medicine, pulmonary medicine and public health. He is the Co-Founder and President of Air for Health, a non-profit organisation aimed at educating medical professionals about the impact of air pollution and climate...

An update on HPV and the vaccination

In recent years, the role of HPV in the development of oropharyngeal cancers has become apparent. Hannah Fox and Vin Paleri contend that while we may not always be able to cure oropharyngeal cancers, vaccination offers our best hope for...