You searched for "genetics"
Surviving oropharyngeal squamous cell carcinoma – does subsite matter?
Human papilloma virus (HPV) status is a known prognostic factor in oropharyngeal squamous cell carcinoma (OPSCC). The eighth edition of American Joint Cancer Committee (AJCC) has modified the TNM staging to reflect this. However, subsite as an independent prognostic factor...
eNOS and OME
The pathophysiology of otitis media with effusion (OME) is multifaceted. The authors tackled the nitrous oxide (NO) and platelet activating factor (PAF) pathways and the genetic polymorphism of endothelial nitrous oxide synthetase (eNOS). DNA analysis by PCR and restriction fragment...
Hereditary haemorrhagic telangiectasia
This is a very nicely written overview of this difficult condition by two expert rhinologists with a tertiary practice. The genetic basis, pathophysiology, diagnosis, natural history and available management options are all discussed. Clearly there is a large spectrum of...
Sulcus vocalis in patients attending voice clinics: A retrospective study
Sulcus vocalis was first described by Giacomini. This includes a variety of anatomic indentations of the vocal fold, ranging from shallow longitudinal furrows to deep vocal cord pits. This retrospective study was conducted at King Saud University between 2006 and...
A higher aspiration for fine needles
Fine needle aspiration biopsy (FNAB) has aided in the diagnosis and management of thyroid nodules for decades. Now a rapid evolution is hoped to benefit an increasing cohort of patients with small nodules and non-diagnostic investigations. This review discusses the...In conversation with Professor Gao Zhiqiang
Prof Zhiqiang, President of the Chinese Society of Otorhinolaryngology, Head and Neck surgery takes us on a journey spanning over a hundred years of ENT in China: A story of an amazing achievement in a country with a population over...Plasticity with cochlear implants: individual factors in the outcomes
Andrej Kral gives us an overview of neuronal plasticity in congenital hearing loss, and discusses why it is core to our clinical interventions in hearing loss and rehabilitation. The brain is born immature and undergoes extensive shaping during early development....The changing landscape for hearing loss therapeutics: novel advances of gene and cell therapies
Recent years have seen advances in hearing loss therapeutics, with novel treatments trialled in humans, and others nearing promising first-in-kind clinical trials. First successful clinical trials for a specific form of genetic hearing loss Very exciting news has emerged in...Laryngology: past, present and future
Two laryngological authorities trace the history of laryngology, from ancient Rome to the modern day. The structure of the vocal folds was a matter of conjecture until the renaissance when anatomists such as Andreas Vesalius and Julius Casserius demonstrated the...
Clinical Manual of Otolaryngology
This book aims to fill the gap that many ‘generic clinical textbooks’ fail to address; the knowledge and skills required to deal with common ear, nose and throat conditions that present to general practitioners and in emergency departments. Its scope...
Basic Fundamentals in Hearing Science
The preface to this textbook explains that its inspiration came from an identified need to replace a previously discontinued hearing science textbook authored by Durrant and Lovrinic in 1995. This was an excellent resource that I used throughout my own...
