You searched for "chemoradiotherapy"

176 results found

Algorithm for malignant otitis externa

Timely detection and effective management of this potentially fatal condition cannot be overemphasised. This study presents 16 cases over 12 months in a tertiary referral centre. Most patients had diabetes and others were immunocompromised due to radiotherapy, immunosuppressive medication or...

Understanding osseointegration for the otologist

Bone conduction implants are hearing devices that require osseointegration to create a stable and reliable interface between the hearing device and the skull to deliver sound to the cochlea. This article reviews the physiology of osseointegration, factors that may lead...

Risk factors for loco regional recurrence for oral SCC

Over 250,000 cases of oral squamous cell carcinomas are diagnosed annually worldwide with 128,000 registered deaths. The authors of this study are from a single institution in Germany and have conducted a retrospective audit of 517 patients with oral SCC...

All about velopharyngeal dysfunction

The velopharynx functionally separates the oral from the nasal cavities. Inadequate or abnormal function of this muscular valve affects speech and swallow. Velopharyngeal dysfunction can be subdivided into insufficiency, incompetence and mislearning. This is a review paper and indeed a...

Malignancies of the Nasal Vestibule

This text is a comprehensive guide to the management of malignancies of the nasal vestibule. The book starts off with a review of the anatomy, patho-physiology and patterns of disease spread for nasal vestibule carcinomas. Of course, no book on...

Invasive differentiated thyroid cancer

The majority of patients presenting with differentiated thyroid cancer have early small disease with excellent long-term outcomes. However, aerodigestive tract invasion is reported in around 10% of case series and is a poor prognostic factor. This article has been authored...

Carotid paragangliomas and their management

Paragangliomas in the head and neck are most frequently associated with the carotid artery, classically at its bifurcation and splaying the internal and external vessels. Despite their commonality at this site, large studies of these rare tumours are still lacking...

Carotid artery involvement with head and neck metastases

This is a retrospective review of 27 patients radiologically diagnosed as having metastases involving the common or internal carotid arteries. All patients underwent a salvage neck dissection with surgical carotid peeling. Thirteen of the 27 achieved loco-regional control, five developed...

Risk factors for post laryngectomy fistula

This is a meta-analysis looking at the postoperative pharyngocutaneous fistula rates following total laryngectomy. The authors ended up with 34 studies with about 2500 patients. The most striking finding was that preoperative radiotherapy was a significant risk factor as well...

No difference upper or lower lip

This is a retrospective review from the Netherlands over a 20-year period to 2009 of squamous cell carcinoma (SCC) of the lip. In total, 979 cases of the lower lip were identified and 126 of the upper lip, with men...

Rare, aggressive pituitary adenomas

This is a review article on published cases of the rare Crooke’s pituitary adenoma. These tumors are usually invasive and may be clinically aggressive; they may be endocrinologically silent or may produce adrenocorticotropic hormone causing Cushing’s disease. They often recur...

Paediatric salivary gland tumours

This is a review article of a rare group of neoplasms that frequently present as painless preauricular mass in older children. There is a wide differential including first branchial arch abnormalities, inflammatory and granulomatous processes. Those masses that are painless,...