You searched for "amplification"

2063 results found

Using evidence and international consensus to guide treatment of thyroid nodules

The authors of this practical review paper highlight a growing issue within thyroid surgery, where high-quality ultrasound has increased the detection of subclinical nodules: what do we do with the patient presenting with an ‘incidental’ thyroid nodule? This has both...

Postoperative radiation in early stage oropharyngeal squamous cell cancer (OPSCC)

There is significant variation in treatment strategies for OPSCC between units. This is largely due to unanswered questions which continue to exist beyond the published literature. We know that human papilloma virus status has a significant influence on prognosis but...

The future: brain imaging for aphasia rehabilitation

Technology offers our patients vast potential, yet the research literature in this area is often technical and difficult to translate to the day-to-day clinical setting. This article aims to review structural and functional imaging methods and discuss how they are...

Evidence for diagnostic role of narrow band imaging in the outpatient setting for head and neck squamous cell carcinoma

Narrow band imaging (NBI) uses light in the blue and green spectrum to differentiate areas of carcinoma from normal or inflammatory tissue. This tertiary referral head and neck unit in Spain used white light endoscopy as initial screening for all...

SPECT-CT imaging improves surgical efficiency in sentinel lymph node biopsy in melanoma

Sentinel lymph node biopsy is used in clinically lymph node negative, primary cutaneous melanoma. A combination of planer lymposcintigraphy using a radiolabelled colloid detected intra-op by gamma probe, and cutaneous injection of blue dye is used. However, with lymphoscintigraphy spillage...

Olfactory ensheathing cells and their safe harvest

This interesting and unique paper not only demonstrates that biopsy of olfactory mucosa in the region of the superior turbinate is a safe procedure but also provides valuable insight into an engaging area of research by a world class team...

Darn it! It’s going to take longer to get good at stapes surgery!

Traditionally, it has been said the learning curve for a particular operation lies between 20 and 30 cases. In stapedotomy, a surgeon is deemed successful and perhaps competent if closure of the air-bone gap (ABG) is reached to within 10dB...

BPPV duration as a predictor for therapy

Benign paroxysmal positional vertigo (BPPV) is one of the most common vestibuar disorders encountered in the neurotology clinic. The majority of cases of BPPV are due to vestibuar lithiasis in the posterior semicircular canal, but there are reports of cases...

Have we reached our limits in endoscopic skull base surgery?

As being an anterior skull base surgeon becomes the aspiration of many ENT trainees, Professor Nicolai gives his personal insights into the future for this exciting subspeciality. Having been directly involved in the evolution of transnasal endscopic surgery (TES) since...

The ear-brain connection in cochlear implant users: learning to listen again

While the cochlear implant (CI) has been a tremendous success in restoring hearing to deaf individuals, the implantation outcome still varies across CI users [1]. Some demographic factors, such as duration of deafness, and peripheral factors, such as electrode placement,...

Unanswered questions in adult ototoxicity associated with platinum-based chemotherapy

Do the potential side-effects on hearing and tinnitus need to be a ‘necessary evil’ of platinum-based chemotherapy? How strong is our evidence base when offering advice to patients and fellow clinicians? David Baguley and his team from the University of...

High definition tractography to identify cranial nerves

It has always been challenging to visualise cranial nerves on traditional imaging as the cranial nerves have a fine structure and complex anatomy. This is especially true regarding the cochlear nerve. In congenitally hearing impaired children, the visualisation of the...