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Can we predict how much benefit patients will get from ESS with a novel monoclonal antibody
Mepolizumab (Nucala) is a humanised IgG1 monoclonal antibody that acts as an IL-5 antagonist. It has been shown to be highly effective in treating severe asthma. It is hypothesised that it will be effective for patients with recalcitrant CRSwNP. This...
CI outcome measures and different languages
Outcome measures for hearing rehabilitation strategies in children are the subject of endless debate. The underlying problem with measuring outcomes in this population is delineating the extent to which development (which is in itself variable) and hearing ability (usually the...
Does use of pectoralis muscle myocutaneous flap (PMMCF) reduce postoperative pharyngocutaneous fistula complication after salvage laryngectomy?
Salvage laryngectomy for recurrent laryngeal carcinoma following failed radiotherapy or chemoradiotherapy is associated with high postoperative complication rate. The primary aim of this paper was to assess whether use of muscle myocutaneous flap (PMMCF) as an interposition graft reduces the...
Endoscopic stapes surgery
This retrospective Turkish study looked at the audiological and surgical outcomes of 40 patients who underwent endoscopic stapes surgery over a three-year period. To assess the learning curve, the patients were divided into two groups based on the date of...
Choline PET-CT: an accurate diagnostic tool for the detection of parathyroid adenoma?
Hyperparathyroidism (HPT) is an endocrine disorder characterised by an increase in the secretion of parathyroid hormone (PTH), with a resulting increase in calcium plasma levels, which can cause renal lithiasis, fractures, and osteoporosis, the most frequent symptoms of the disease....
SNOT-25 to assess CRS - a new tool
The SNOT-22 is a well-established validated instrument, designed to evaluate the rhinosinusitis-specific health status and health-related QOL, however makes only one broad reference to productivity. The objective of this paper is to evaluate a modified SNOT-25 created to better assess...
Assessing post-extubation dysphagia on the intensive care unit
The incidence of post-extubation dysphagia (PED) is reported to be about 12% in the general ICU population and around 18% in patients admitted to ICU as emergencies. PED was found to be an independent predictor of 28-day and 90-day mortality....
Relapse after bi-maxillary surgery in a class III malocclusion
This study analysed 90 patients who underwent a bi-maxillary osteotomy for a class III malocclusion. There were 30 in each of three groups of patients based upon the Frankfort mandibular plane angle (FMA). They were divided into: greater than 32°,...
Conductive hearing loss and temporal processing
This Turkish study looked at the effect of using hearing aids on auditory temporal processing (the ability of the hearing system to process the temporal properties of a sound stimulus in a certain period of time) in conductive hearing loss....
Do adhesions actually cause nasal blockage?
All of us who perform nasal surgery are familiar with the disappointing presence of nasal adhesions (NA) or synechiae in our postop patients. These can often lead to patients deriving less perceived benefit from their surgery than that which they...
Perioperative management of the head and neck cancer patient
The perioperative care of patients with head and neck cancer is complex and requires significant preoperative planning and patient education. The issues include analgesia, antibiotics, stoma and wound care, general and chest physiotherapy, thromboprophylaxis and nutrition. This article provides a...
