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Laryngeal oedema as a side-effect of tyrosine kinase inhibitor therapy

Tyrosine kinase inhibitors (TKIs) such as Imatinib are increasingly being used to treat haematological and solid malignancies. These agents have revolutionised the treatment of chronic myeloid leukaemia in particular. Although better tolerated than most conventional chemotherapy drugs, multiple side-effects have...

A drug to prevent hearing loss caused by ototoxic therapeutics

This editorial briefly highlights the progress made in discovering a compound named ORC-13661, which shows the potential to alter the response of hair cells to ototoxic medication. In the late 1980s, inner hair cells that were lost secondary to noise...

Reducing readmission rates after transsphenoidal pituitary surgery

This retrospective study provides an outpatient care pathway to screen and manage delayed hyponatremia which the study identified as the primary cause of readmission following transsphenoidal pituitary surgery. Of the 303 patients who were studied, 27 were readmitted within 30...

Hearing intervention to prevent dementia

People with hearing impairment have an increased risk of incident all-cause dementia proportional to the severity of loss compared to those with normal hearing. Treating hearing impairment may therefore serve to slow or prevent the onset of cognitive decline. This...

Aided speech auditory brainstem response

Auditory brainstem response (ABR) is commonly used for hearing screening and is considered as one of the important means of objective audiometry. Speech ABR is a relatively new concept and is regarded as a marker of speech encoding at the...