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1887 results found

Can we predict how much benefit patients will get from ESS with a novel monoclonal antibody

Mepolizumab (Nucala) is a humanised IgG1 monoclonal antibody that acts as an IL-5 antagonist. It has been shown to be highly effective in treating severe asthma. It is hypothesised that it will be effective for patients with recalcitrant CRSwNP. This...

OSA is neuroprotective!

This interesting study supports the hypothesis of the protective effects of obstructive sleep apnoea (OSA) against ischemic events like stroke. The authors evaluated the impact of OSA with the presentation, hospital course and outcomes of patients with subarachnoid haemorrhage (SAH)....

Swallowing it whole: the physical and psychological consequences of dysphagia

Living with dysphagia in the real world can be extremely challenging, both practically and psychologically. Long-term changes in taste due to chemo-radiation treatment for head and neck cancer, fatigue due to Parkinson’s disease, and physically impaired structures due to stroke...

How long is too long? Waiting times for speech and language therapy

Waiting lists are a reality of clinical practice, and many health and social care professionals become used to having to cope with this. The authors of this paper addressed this issue by examining written submissions to the 2014 Senate Inquiry...

Is there a need for magnetic resonance imaging six-month post-radiosurgery for vestibular schwannoma?

With advances in imaging and radiation technologies, small, slowly growing vestibular schwannomas (VS) are treated primarily with either observation or stereotactic radiosurgery (SRS). Routine magnetic resonance (MRI) scans with gadolinium are obtained six months and one year after SRS in...

Patient factors associated with spontaneous CSF leak

This article highlights the role of obesity, sleep apnoea and raised intracranial pressure as linked pathologies in the aetiology of the spontaneous cerebrospinal fluid (sCSF) leak. The authors link sCSF leak with obesity and comment on sCSF leak incidence increasing...

Is the greater auricular nerve important in parotid surgery?

The greater auricular nerve (GAN) is often partially or totally sacrificed during parotidectomy procedures. This was a retrospective study comparing auricular sensation and quality of life in patients that either had their GAN preserved or sacrificed. In the shortterm, patients...

Delays in oral cancer

This is a review from Canada where they attempt to relate delays in oral cancer presentation to treatment and the impact on stage, diagnosis and survival. They recognise that potentially the most significant delay is between the patient first noticing...

Chronic rhinitis endotypes

Chronic rhinitis (CR) is common with up to 30% of the population affected, with a significant impact on quality of life. CR includes several phenotypes with different pathogenesis including allergy, autoimmune, age, occupation, pregnancy, neurogenic and drugs. Such variation means...

How many friends will you have after a TBI?

Friendships are key to reducing stress and improving morale and social support. Loss of friendships after a traumatic brain injury (TBI) can have a significant impact on these areas of a person’s life. There is little in the research literature...

Deglutition in pharyngolaryngectomy patients

Circular defects after total pharyngolaryngectomy present a reconstructive challenge. In this study, the authors compared the swallowing results after three reconstructive techniques: free forearm flap, free jejunal loop and folded pectoralis major flap. Forty-six patients were included and were evaluated...

An understandable backup

This small study comparing the auditory temporal processing of seven younger adults with that of seven older adults does not show anything breathtakingly new in its conclusions. After the assessment to rule out compounding factors such as middle ear pathology,...