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Discovery in the genetics of complex disease: Otitis media
Otitis media (OM), a common disease of childhood, is considered to be a complex trait with multiple genetic and environmental factors expected to contribute to a child’s risk of developing recurrent acute OM (rAOM; ≥3 episodes in 6 months or...
Misophonia
Decreased sound tolerance is a common audiologic complaint. Unlike the classic characteristics of hyperacusis whereby a patient is sensitive to the frequency or volume of a sound, misophonia is a strong emotional and psychological reaction to a sound with a...Erasmus Darwin and the larynx – but why is it where it is and when?
Charles Darwin’s grandfather was not only on to where we all came from by the end of the 18th century, but dared to declare it in verse whilst resident in Lichfield Cathedral Close. This needed exceptional temerity, since not only...
Basic Concepts of Clinical Electrophysiology in Audiology
Signal averaging principles have been around since 1875, but their application in medicine to enhance biologic signals was first made in 1947 for improved detection of electroencephalographic signals. It took a few more years until the first electrophysiological studies were...
