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The hippo and the nose

Chronic rhinosinusitis with nasal polyps (CRSwNP) leads to histological changes including thickening of the basilar membrane and epithelial proliferation. Molecular mechanisms underlying these changes are still not fully clear. A signalling pathway called the hippo with Yes‐associated protein (YAP) as...

Gardasil vaccination for laryngeal RRP – an update

This paper reports the results of a follow-up study investigating the possible role of adjuvant Gardasil vaccination in patients with recurrent laryngeal papillomatosis. The preceding study – also published in the Journal of Voice (2017) – reported the changes in...

From Listening to Language: Comprehensive Intervention to Maximise Learning for Children and Adults with Hearing Loss

How does one build a two-storey house? Start with a firm foundation, followed by a strong structure. Only then can the floors and attic be added. Madell and Hewitt provide practitioners with this same blueprint to facilitate optimal outcomes for...

Robotic surgery for squamous cell cancer: the new frontiers

Although the da Vinci platform was FDA approved for early-stage oropharyngeal cancers, the indications have expanded. In this article, John Hardman explains how surgeons, with greater understanding of the strengths and limitations of robotic surgery, have systematically set out to...

A comparison of two different audiology roles in Denmark and the United Kingdom

The World Health Organisation (WHO) estimates that there are over 360 million people with a disabling hearing loss in the world. Disabling hearing loss is considered to be a loss of greater than 40 decibels (dB) in the better hearing...

Superior semicircular canal dehiscence: transmastoid obliteration

Sometimes patients with dizziness turn out to have slightly more unusual causes of their problem. Thomas Milner and Georgios Kontorinis describe their technique for managing patients who have a diagnosis of superior canal dehiscence as an identified cause of their...

Airway stenting in paediatric ENT

Although experience in the use of airway stents in adults is considerable, their use in children is more recent and more limited. Cláudia Schweiger and Michael J Rutter provide an overview of stents and their use in paediatric airway. Stenting...

The structure and function of DNA

DNA structure and replication Genetic information within multicellular organisms, including man, is stored in molecules of deoxyribonucleic acid (DNA), which reside within the chromosomes of each cell nucleus. A DNA molecule consists of two very long chains, or strands, of...

Double suspension sutures for obstructive sleep apnoea

This study examines the benefit of an operation that targets the lateral pharyngeal wall. The double suspension sutures are, in essence, a suture through the palatopharyngeus muscle which is then tied around the hamulus in the retro molar area. This...

Allergen immunotherapy and allergic rhinitis – EAACI guideline 2017

Allergic rhinitis (AR) is a common chronic childhood disease with considerable social burden and impact on quality of life, frequently necessitating treatment with various combinations of antihistamines and corticosteroids. The allergen immunotherapy (AIT), sometimes known as desensitisation therapy, can modify...

Role of interventional neuroradiology in otorhinolarygological pathology 
– a brief review

Introduction Since its advent in 1964 when Dotter percutaneously dilated a stenosed femoral artery [1], interventional radiology has undergone tremendous advancement in both imaging and devices that have enabled the operator (interventional radiologist) to access very distal small vasculature and...

The UK otolaryngology trainees’ lived experience during the COVID-19 pandemic

Much has been published on the concerns and real impact of the pandemic on surgical training. In this article, colleagues from the Association of Otorhinolaryngologists in Training (AOT) in the UK share the experiences of their membership. We invite our...