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The structure and function of DNA

DNA structure and replication Genetic information within multicellular organisms, including man, is stored in molecules of deoxyribonucleic acid (DNA), which reside within the chromosomes of each cell nucleus. A DNA molecule consists of two very long chains, or strands, of...

NHS collaboration and partnership with the pharmaceutical and medical devices industries

Historically the relationship between industry and the NHS has been a cautious one. Both sides have typically worked with only partially disclosed agendas, under a pervading fear of finding themselves on the wrong end of a win-lose negotiation. Things have...

Surgical management of sleep disordered breathing

Snoring and sleep-disordered breathing are often described as multi-level problems, and different surgical procedures are required to treat the various sites of airway narrowing and/or collapse. Jonathan Hobson gives us an eloquent run-through the various options available to the ENT...

What’s in a name?

Kate Granger is a doctor and the founder of the #hellomynameis campaign; she is also a cancer patient. In this article she explains why she started the campaign, and why patient-centred care starts with an introduction. Chris and me the...

Thyroid cancer – the last decade

Professor Ashok Shaha describes the evolution in the treatment of thyroid cancer that he has witnessed over the last decade and the invaluable progress made by himself and others, from their contributions to staging systems and guidelines. Nuances and paradigm...

Multi-channel cochlear implants: past, present and future

Forty years since the first multi-channel devices were implanted, who better than Ingeborg Hochmair, who has been a key figure throughout their evolution, to offer her thoughts on the past, present and future of multi-channel cochlear implants? Read on for...

Achieving consensus on candidacy for cochlear implantation

The British Cochlear Implant Group’s candidacy working group recently ran a national exercise, working towards a consensus on candidacy for cochlear implantation in the UK. Padraig Kitterick and Debi Vickers were instrumental in this exercise, and in the article below,...

Laryngeal papillomatosis

Laryngeal papillomatosis remains one of the most frustrating conditions seen by laryngologists. Sam Majumdar gives us an overview of the current science and clinical practice. Human papilloma virus is a small (> 8kb) double stranded DNA virus with approximately 200...

European power women in otolaryngology: a focus on Laura Viani, Ireland’s first female otolaryngologist

Professor Laura Viani is a Consultant Otolaryngologist at Beaumont Hospital and Temple Street University Children’s Hospital and has been a member of Council of the Royal College of Surgeons of Ireland for the last 17 years. As the first female...

What does functional neuroimaging tell us about tinnitus?

One of the most common causes of tinnitus is noise exposure, be that either cumulative day-to-day exposure over a lifetime or experience of acute noise trauma such as a loud concert or shooting incident. Observational data indicate that up to...

Questionnaires to measure tinnitus severity

The handicap associated with tinnitus can arise from any combination of stress, anxiety, depression, emotional distress, insomnia, difficulties concentrating, or impairments in quality of life or everyday functioning. Measuring such handicap and determining clinical need is therefore far from trivial....