You searched for "therapeutics"

445 results found

Sublingual house dust mite immunotherapy

House dust mite immunotherapy in allergic rhinitis was shown to be effective in trials with a relatively small number of participants. The authors of this study performed a multicentre double-blind randomised controlled trial to investigate effects of house dust mite...

Still not smelling

Post-Covid anosmia/hyposmia is a troublesome persistent symptom for lots of patients. Management is still elusive. This was a nationwide survey of ENT practitioners. Of the 715 surveyed members, only 7.4% responded. Most performed a nasal endoscopy, 60% ordered an MRI...

Previous radiotherapy does not cause worse outcomes in patients with differentiated thyroid cancer

Radiation exposure from nuclear incidents, especially in childhood, is known to increase the risk of thyroid cancer. This large retrospective study from the Memorial Sloan Kettering Cancer Centre sought to determine if thyroid cancers in patients with prior exposure to...

AM and the neck

Infections with atypical mycobacteria (AM) are increasing, especially with the decline in BCG immunisation. The most frequent presentation is a lymphadenopathy in an immunocompetent child. This poses a difficult diagnostic challenge if the clinician is not aware of this entity....

Risk factors for TORS treatment failure in HPV-related oropharyngeal cancers

HPV-related squamous cell cancers are an increasingly common cause of malignancy in the oropharynx. There is evidence that these cancers are associated with a significantly improved overall survival compared to conventional HPV-negative tumours. The optimal treatment for such cancers is...

T1 lip cancer and cervical lymph node metastases

The management of large lip squamous cell carcinoma (SCC) (T2, T3, T4 tumours) or those with nodal disease is well established. However the management of T1N0 tumours is controversial due to the assumed low risk of occult lymph node metastases....

Sushruta and Indian rhinoplasty

Vijay Pothula explains rhinoplasty’s roots in ancient Indian Ayurvedic medicine, and how it was introduced to the Western world. In 1794 The Gentleman’s Magazine published a surgical operation which was long established in India but unknown in Europe [1]. A...

British Academy of Audiology Higher Training Scheme – Head of Service and trainee perspectives

For Jan/Feb 2022, we continue with the topic of the British Academy of Audiology Higher Training Scheme. We hear from Jane Beavan, Clinical and Professional Lead for Audiology/Clinical Scientist in Audiology, and Kim-Maree Collings, Senior Audiologist, from the Countess of...

The search for pharmacological treatments for hearing loss and tinnitus

Where are we in our search for a hearing restoration grail? Nicola Robas leads us through the map pieces discovered in creating a pharmaceutical answer to hearing loss and tinnitus. Together, hearing loss and tinnitus affect over one in six...

Loss of smell after COVID-19: a view from the patient forums

Patient advocate, Chrissi Kelly, founder of AbScent, talks about how the pandemic has changed the way we think about smell loss. The high prevalence of chemosensory impairment as a result of the SARS-CoV-2 virus has shone a much-needed spotlight on...

A therapeutic algorithm for tracheoesophageal periprosthetic leakage

Tracheoesophageal voice prosthesis leakage can be intravalvular (more common) or periprosthetic (focus of this study). The authors studied the causes of periprosthetic leakage among 115 patients attending for voice prosthesis management (1374 clinic attendances) treated between December 2014 to December...

Not just the scissors: the story of Myron Metzenbaum

Myron Metzenbaum was born in Cleveland, Ohio (USA) in 1876, the fourth of nine children. As a young man, he worked in the family’s linen store, where his father was well known to be very kind to the less fortunate...