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What you need to know about recent advances in genetics of hearing loss in the newborn

Identifying the underlying genetic cause of hearing loss in newborns can improve dramatically the early diagnosis and appropriate intervention. Hearing loss is the most common sensory disorder at birth, affecting approximately two out of 1000 newborns [1]. Congenital impaired hearing...

Electronic nicotine delivery systems (e-cigarettes): what you need to know

As an aid to stopping smoking e-cigarettes may have a role, but they are heavily promoted by industry as a leisure pursuit and desirable fashion accessory. Sneh Biyani and Craig Derkay gives a thorough account of what we know about...

Microneedles enable inner ear precision medicine

Developing safe, reliable and efficient ways to deliver therapeutics into the cochlea is a key challenge. In this article, the authors share their work to develop microneedles to address this challenge. The era of precision medicine of the inner ear...

Freud’s Friend, Fliess

Wilhelm Fliess, a Berlin rhinologist, was for many years Sigmund Freud’s closest friend and confidant. He was born in Poland in 1858. In 1887, he visited Vienna for postgraduate studies, and met the famous psychoanalyst, Freud [1]. They were immediate...

History of ENT - Freud's Friend, Fliess

Wilhelm Fliess, a Berlin rhinologist, was for many years Sigmund Freud’s closest friend and confidant. He was born in Poland in 1858. In 1887, he visited Vienna for postgraduate studies, and met the famous psychoanalyst, Freud [1]. They were immediate...

Murder most foul, strange and unnatural

Hamlet, written by William Shakespeare at the very beginning of the 17th century has definite otological interest. The whole play is about young Prince Hamlet’s revenge for his father’s murder. The king is killed by Hamlet’s wicked uncle, who then...

History of ENT - Murder most foul, strange and unnatural

Hamlet written by William Shakespeare at the very beginning of the 17th century has definite otological interest. The whole play is about young Prince Hamlet’s revenge for his father’s murder. The king is killed by Hamlet’s wicked uncle, who then...

Genetic discovery using animal models: presbyacusis

By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...

Changing behaviour with a human factors approach

The Francis Report (2013) identified multiple problems relating to the safety culture of Stafford Hospital in the period 2005 – 2009, as well as serious failings in the supervisory and regulatory systems of the NHS. Particular criticism was directed at...