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Laryngeal Cancer: Clinical Case-Based Approaches
This book, published by Thieme, provides a lot of information in a compact size. I enjoyed reading the book as it has an international list of authors and contributors from South America, USA, Europe and Asia which gives it an...
Laryngeal oedema as a side-effect of tyrosine kinase inhibitor therapy
Tyrosine kinase inhibitors (TKIs) such as Imatinib are increasingly being used to treat haematological and solid malignancies. These agents have revolutionised the treatment of chronic myeloid leukaemia in particular. Although better tolerated than most conventional chemotherapy drugs, multiple side-effects have...
Preserving hearing in NF2 patients
Neurofibromatosis type 2 (NF2) is known to result in bilateral hearing loss, even when there is no significant tumour growth. The cause is postulated to be multifactorial: stretching and compression of the cochlear nerve by the tumour, impairment of labyrinthine...What’s happened since the European position paper on nose and sinus tumours?
The management of malignant sinonasal tumours has gone through radical changes in recent years. Prof Valerie Lund gives us an update based on her upcoming talk at IFOS. In 2010 when we published the European position paper on ‘endoscopic management...Cancer genetics and signalling pathways in ENT – a review and discussion of how this can be applied to rare tumours
Introduction Cancer cases continue to increase worldwide, and head and neck cancer is a major global health issue, with an estimated global burden of over 630,000 new cases and over 350,000 deaths per year [1]. The term ‘head and neck...
BAHA loading two weeks after implant insertion
The time thought necessary for sufficient osseointegration to occur to enable use of a BAHA has reduced from months to a few weeks. This paper further reduces this timescale to two weeks in patients with healthy bone and soft tissue...
Speech predictors after glossectomy
This is a cross-sectional study from India where 69 patients were assessed for speech intelligibility and phonetics using an assessment tool in the local language. Volume defects were classified into thirds and the location of this defect noted. Not unsurprisingly,...
Brown classification of a maxillary defect and prognosis
This is a retrospective study from Peking over the 10-year period, 2000-2010, for 137 patients with maxillary squamous cell carcinoma assessed. The overall survival rate was comparable with other studies at 64.8%. The most common Brown maxillary defect was 2b...
Treatment outcomes and dose rate effects following gamma knife stereotactic radiosurgery for vestibular schwannomas
Gamma knife radiosurgery (GKRS) is one of the definitive stereotactic radiotherapy treatment modalities for vestibular schwannoma (VS) management. Its efficacy depends on the cobalt-60 source which has a half-life of 5.26 years. According to the study authors, the actual rate...
Delays in oral cancer
This is a review from Canada where they attempt to relate delays in oral cancer presentation to treatment and the impact on stage, diagnosis and survival. They recognise that potentially the most significant delay is between the patient first noticing...
