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Systemic agents in thyroid cancer

For those patients who have disseminated or unresectable thyroid cancer, Dr Arabella Hunt and Dr Kate Newbold review systemic treatments, their differences, toxicities and outcomes. Thyroid cancer is the most common endocrine malignancy. It is subdivided into differentiated (papillary, follicular...

In conversation with Ray Clarke: Scott-Brown – The Editors’ view…

Ray Clarke. How did you get involved in the forthcoming Scott-Brown ? How does one become editor of a textbook? Editors are approached and appointed by the publishers, but of course publishers will take advice and soundings from within the...

Scientific advances in mapping syndromic hearing loss

From more than 22000 genes that we humans have, approximately 3000 genes are associated with human communication. There are tens of syndromes which have been identified to be accompanied by hearing loss. Disorders of almost every organ of the body...

Drug side-effects on audiological and vestibular testing

Are they a malingerer? Or perhaps they are inattentive? It may be their drugs! Robert DiSogra considers the side-effects of medication on the test subject. The audiogram serves many purposes in clinical practice. For the audiologist, it helps to differentiate...

Functional Endoscopic Sinus Surgery (FESS) - Part 2

In the first of this two-part series, Martyn Barnes and colleagues discussed indications for functional endoscopic sinus surgery (FESS), the surgical objectives and techniques, patient expectations and the risks of surgery [1]. In this second and final part, the authors...

Singing after laryngectomy: Shout at Cancer

Thomas Moors is an ENT junior doctor with a background in music and singing. Combining these interests, he has set up a charity to help patients who have had a laryngectomy. He has achieved considerable public attention, and he tells...

The making of a paediatric airway surgeon: In conversation with David Albert

Michael Kuo interviews David Albert to find out what drew him to paediatric airway surgery, the mentors who shaped his surgical approach, and to ask his advice for budding young paediatric airway surgeons. David Albert. When did you first get...

How sight shapes sound: cross-modal plasticity and cochlear implantation

Visual cues support auditory recovery after cochlear implantation, with evidence showing cross-modal plasticity enhances speech perception and rehabilitation outcomes. Traditionally, clinical guidance around cochlear implantation has been shaped by a key concern: that reliance on visual communication, particularly speechreading, might...

Central auditory changes in SNHL

Robert Harrison discusses some of the most obvious ways in which cochlear hearing loss has central consequences. It is convenient to classify hearing loss according to the most obvious site of lesion, for example, conductive, cochlear, retro-cochlear, or central hearing...

Plasticity with cochlear implants: individual factors in the outcomes

Andrej Kral gives us an overview of neuronal plasticity in congenital hearing loss, and discusses why it is core to our clinical interventions in hearing loss and rehabilitation. The brain is born immature and undergoes extensive shaping during early development....

Combined use of a hearing aid and a cochlear implant: a case study

When multi-channel cochlear implants (CIs) were first introduced in the 1980s, their use was restricted to people who derived no benefit from conventional amplification. Over the past three decades, however, the criteria for CIs has been relaxed considerably, and it...

Targeted CMV screening and hearing management of children with congenital cytomegalovirus infection

Congenital cytomegalovirus (cCMV) infection is a common congenital infection and is the leading infectious cause of sensorineural hearing loss (SNHL) in children. Prof Karen Fowler discusses current research and the exciting future of screening for cCMV in newborns. Figure 1....