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CRSwNP, another monoclonal antibody
Interleukins 4, 5 and 13 were shown to be important factors in type 2 inflammation, which characterises chronic rhinosinusitis with nasal polyposis (CRSwNP). In CRSwNP non-responders and those who recur short after-surgery monoclonal antibodies might be an answer. Examples include...
Antioxidants for bacterial rhinosinusitis
This Turkish laboratory animal-based study looked at the effects of alpha-lipoic acid on inflammation, oxidative status, and tissue integrity in an animal model of experimentally induced acute rhinosinusitis and to compare these effects with antibiotic treatment using cephalosporins. Alpha-lipoic acid...
A new hope for post-COVID olfactory loss?
Does anyone remember COVID? It seems that what happened between 2019 and 2021 is all but forgotten about. Aside from it cropping up on news feeds occasionally and a few out-of-date automated phone messages that start off with ‘During the...
Ethnic inequalities in hearing aid use
Recent events, including the COVID-19 pandemic, have once again highlighted health inequalities experienced by people from ethnic minority backgrounds. Our Editors’ Choice paper shows that there are inequalities in hearing aid use and includes the stark finding that ethnicity is...
Does middle turbinate resection affect olfaction in endoscopic transsphenoidal surgery?
The middle turbinates (MT) are sometimes partially resected during endoscopic transnasal transsphenoidal pituitary surgery to improve surgical access. Some outfracture the middle turbinates instead. This article presents results of the first prospective randomised study, investigating the effects of such surgery...
Which bit of our brains do we need to recognise fear, disgust and happiness?
Recognising other people’s emotions is a useful life skill for human interaction in both social and vocational situations. Yet there remains significant debate about which areas of the brain are required to enable us to read and understand these facial...
Does turbinoplasty outcome vary in the presence of allergic disease?
This well organised study from Australia looks at inferior turbinoplasty outcomes in patients with allergy and non-allergic rhinitis who have become refractory to medical treatment. There were 190 patients undergoing turbinoplasty with or without septoplasty assessed in this case-control study...
Gardasil vaccination as an adjuvant treatment for established recurrent laryngeal papillomatosis in male adults - does it stimulate an immune response?
Recurrent respiratory papillomatosis (RRP) is well known to be caused by infection with the human papilloma virus (types 6 and 11). Recurrence after surgical removal is common and potentially frequent and severe. Previous research has established that many patients with...
Is Dymista® useful for paediatric allergic rhinitis?
Allergic rhinitis (AR) affects up to 14.6% of the paediatric population. Whilst a recent Cochrane review has considered the evidence for intranasal corticosteroids as `weak and unreliable’ in paediatric AR, this product is a novel formulation combining Fluticasone and Azelastine...What does functional neuroimaging tell us about tinnitus?
One of the most common causes of tinnitus is noise exposure, be that either cumulative day-to-day exposure over a lifetime or experience of acute noise trauma such as a loud concert or shooting incident. Observational data indicate that up to...
