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The future of biologics?
This paper takes a deep dive into how eosinophilia affects the responsiveness of the host to the two monoclonal antibodies mepolizumab and bendralizumab, both of which are active against IL5. We know that eosinophils are attracted and trapped into the...
A review of DISE classification systems
This article looks at the wide variety of classification systems currently available for interpreting drug induced sleep endoscopy (DISE).The fact that there are so many classification systems, suggests that there is: A) a lot of disagreement about how DISE should...
Pre-habilitation in head and neck cancer – a literature review to guide best practice
Curative treatment of head and neck cancer (HNC) often requires surgery; however, outcomes are impacted by the complexity of the surgery and the patient population. Increasingly ‘Enhanced Recovery After Surgery’ (ERAS) protocols are being used to maximise patient outcomes and...
Is major ear surgery financially viable?
It is difficult to ignore the present reality in the NHS that understanding clinical coding is perhaps of more relevance to the practising clinician than the human genome! Clinician engagement is becoming more essential to protect patient care and maximise...
Contemporary Rhinology Science and Practice
Contemporary Rhinology Science and Practice is an excellent textbook that provides a comprehensive and up-to-date approach to various rhinology and skull base conditions. This text expertly integrates both applied science and clinical aspects, making it an invaluable resource for practitioners...
Audiological symptoms in children with 18q deletion
18q deletion is a rare genetic condition that occurs in approximately one in 40,000 live births. Those born with this deletion often are born with a range of symptoms, including developmental delay, facial dysmorphism, autoimmune disorders and hearing loss. The...Ultramarathons, frostbite and running with wolves
“I could just keep going when most sane people would stop”- the secret to success in head and neck surgery? In August 2015 I crossed the finish line of La Ultra - The High. A small camp of tents and...St Blaise - patron saint of the throat
In a previous article, we looked at some interesting legends surrounding patron saints of the ear and hearing [1]. As we celebrate the Feast Day of St Blaise of Sebastia on 3 February, we hear some fascinating tales and myths...
Listening and Spoken Language Therapy for Children with Hearing Loss
I’d like to start this review with a disclaimer – I don’t deliver speech and language therapy but am interested in how speech, language and communication are developing in the children we see with hearing loss within audiology. I found...
Factors influencing transformation of laryngeal dysplasia to malignancy in a 10-year review
Laryngeal dysplasia has a propensity to change into malignancy, the generally reported rate of this being about 14%. In this retrospective study of 125 patients, the authors have assessed the severity of dysplasia in relation to the incidence and time...
Role of imaging in unilateral sensorineural hearing loss
Recent understanding of the significance of unilateral hearing loss in children for language development calls for extensive investigations and early rehabilitation. This retrospective study of 90 children with unilateral hearing loss with high resolution CT scans and MRI revealed that...
