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The fatal illness of Frederick the Noble

Sir Morell Mackenzie is acknowledged as the ‘Father of British Otolaryngology’. He was the leading throat specialist of his time and one of the founders of the Journal of Laryngology and Otology in 1887. He studied in Paris, Vienna and...

Could OtoRecall transform ENT learning?

Training continues to change and evolve in the face of changing working practices and, of course, the impact of unprecedented events like the pandemic. The basics remain important for safe practice as training and work continue to evolve; innovative tools...

The polyp shrinker

Inflammatory markers, including T2 cells beta common (βc) cytokines IL-3, IL5 and granulocyte-macrophage colony-stimulating factor (GM-CSF), are known to play an important role in chronic rhinosinusitis with nasal polyps (CRSwNP). CSL311, a monoclonal antibody (mAb), was developed to target human...

What we need to know about the new frontier of inner ear therapies

This is an interesting and topical review of the emerging biotechnology and pharmaceutical solutions for hearing loss and related conditions such as tinnitus. This paper suggests we are on the cusp of a very large step-change in the way we...

Workplace culture: observations of audiology in Northern England and Western Australia

Working with a diverse workforce and coping with transition forced me to consider the importance of cultural differences in the workplace. Only by trying to understand these differences can you understand others’ behaviour and what motivates the team. I have...

The role of significant others in hearing aid adoption

Presbycusis, or age-related hearing loss, is one of the most common conditions affecting older adults and its prevalence is found to increase with age. Over the years, amplification technology has advanced significantly from analogue to digital signal processing. Despite this,...

Changing perceptions in head and neck cancer management caused by quality of life issues

Sir Felix Semon was an outstanding clinician and exceptional laryngologist. The money raised by donations from his colleagues on his retirement in 1909 was used to establish the London University’s Semon Lecture. Semon’s Obituary in the BMJ, reads: “In Semon's...

Which cross-over frequency is best for electro-acoustic stimulation?

Advances in technology and improved soft surgical techniques have led to individuals with better hearing thresholds, especially at the low frequencies, becoming candidates for cochlear implants (CI). Surgeons are more confident that residual hearing can be preserved thus making those...

Suspect the unsuspecting in thyroid cancer

This article reminds readers of how often invasive thyroid disease can appear, as the symptomatology is minimal. Noticeable airway symptoms appear after 50% of the airway is involved and surgeons can often fall in the unsuspecting trap of discovering locally...

What is the evidence for duration of antibiotic prophylaxis in head and neck free-flap cases?

The topic of this systematic review is one which is commonly heard in discussions between microbiologists and head and neck surgeons – what is the evidence for antibiotic prophylaxis in clean-contaminated free-flap cases, and crucially, how long should antibiotics be...

Does transoral robotic surgery improve outcomes among patients with head and neck cancer of unknown primary?

A tonsillectomy and tongue base mucosectomy is becoming increasingly accepted as the optimal surgical intervention to aid in identifying the primary source of a p16+ / HPV-related squamous cell carcinoma (SCC) of unknown origin, given that this disease almost exclusively...

Patient reported outcomes improve if antibiotic choice is directed from endoscopic culture results in chronic rhinosinusitis

The use of antibiotics in chronic rhinosinusitis (CRS) has been established as part of the EPOS guidelines, as has the role of taking swabs for microbiology culture. There has not been much literature however on whether tailoring antibiotics in response...