You searched for "Genetic"
To montelukast or not to montelukast
Both histamine and cysteinyl leukotrienes play an important role in both seasonal allergic rhinoconjunctivitis (SARC) and asthma. A combination therapy against both was shown to give benefit both in vitro and in vivo. Authors wanted to test the efficacy of...
Updates on current evidence for biologics in chronic rhinosinusitis
For a comparatively short piece, this article manages to pack in a lot of important information about a complex emerging area of rhinology – immunologically targeted therapy (biologics). Immunologically targeted therapy is a rapidly progressing and expanding domain which is...
Thyroidectomy patient survey regarding voice outcomes
One of the common adverse effects following thyroid surgery is a change in voice, which may be related to iatrogenic injury to the recurrent laryngeal nerve or superior laryngeal nerve during surgery or by direct cancer involvement. The burden of...
Bespoke is best for children with communication difficulties
Children with communication difficulties can benefit from augmentative alternative communication (AAC) aids to support them in daily interaction, as well as in developing milestones. One of the most difficult aspects of choosing a device is not only meeting the child’s...
Risks of tracheostomy in head and neck cancer
Tracheostomy is associated with several complications, with rates quoted as high as 8-45%, including: bleeding; displacement; obstruction; surgical emphysema; pneumothorax; fistulae and failure to decannulate. There are now many studies that confirm the increased length of stay and complications of...
Is dissection of level IV necessary in patients with negative neck oral cancer?
Supraomohyoid neck dissection (SOHND) refers to the removal of lymph nodes contained in levels I-III and is currently referred to as a selective neck dissection levels I-III. This type of neck dissection has been frequently used in the management of...
Online group therapy is easier but is it better?
Aphasia is a communication disability caused by stroke, brain injury or dementia. People with aphasia benefit from both the emotional and communication support that group therapy can provide, yet there can be many barriers to accessing this type of intervention,...
Sudden sensorineural hearing loss – who will get better?
Idiopathic sudden sensorineural hearing loss (ISSNHL) is a rare but potentially devastating condition. For patients presenting with this condition, prognosis is of paramount importance. Wu et al begin to address this issue by retrospectively studying 17 potential prognostic factors for...
Advances in auditory implants
This article provides an overview of auditory implants. Implanted auditory devices may be classified into bone conduction implants (BCI) and active middle ear implants (AMEI) that stimulate cochlear hair cells, and cochlear implants (CI) that stimulate neural structures. CIs bypass...
How best can we manage Samter’s Triad/AERD?
The classic ‘Samter’s Triad’ of asthma, chronic rhinosinusitis with nasal polyposis (CRSwNP), and aspirin sensitivity is now referred to as aspirin-exacerbated respiratory disease (AERD) or non-steroidal anti-inflammatory-exacerbated respiratory disease. We often come across in our rhinology setting, patients with recalcitrant...
Management of patients with advanced otosclerosis
This paper discusses the management options of advanced otosclerosis. There are several definitions for advanced otosclerosis in the literature but, more recently, the diagnosis of advanced otoscletosis has been reserved for patients who have less than 30% aided speech discrimination...
