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Genetics WG4. Improving diagnosis and drug development through the genetic understanding of tinnitus subtypes: a TINNET endeavour
Christopher R Cederroth and Jose Antonio Lopez-Escamez explain how progress is being made to investigate the contribution of genetic factors to tinnitus, including a subtype of ‘extreme’ tinnitus in Ménière’s disease. Genetics WG4 is working towards determining the genetic basis...
Cochlear implants in Ménière’s disease
This retrospective review firstly reminds us that a cochlear implant (CI) is possible with Ménière’s disease (MD) and provides a good account of what can be expected with a CI in patients with MD. Twenty MD patients who underwent cochlear...
The unknown primary again
In this retrospective study of 35 patients, the authors followed a systematic protocol for the detection and management of malignant cervical lymph nodes without an apparent primary lesion. Although their one, three and five year survival results are consistent with...
Cochlear implantation in elderly candidates and effect on quality of life
The authors aimed to assess the improvement in quality of life (QoL) of cochlear implant patients over 60 and its relation to audiometric benefits. An observational retrospective study was conducted on 26 individuals older than 60. The outcome was compared...
Extranodal natural killer / T-cell lymphoma in the head and neck
The authors present a retrospective single institution review of patients with a very rare variant of non-Hodgkin lymphomas (NHL). They report on the occurrence, clinical course and outcomes of their patients with natural killer / T-cell lymphoma (NKTCL) nasal type....
Facial paralysis risk factors in benign parotid surgery
The literature shows that the risk of facial paralysis following benign parotid surgery can be as high as 57% for temporary weakness and 7% for permanent facial nerve damage. It is generally thought that the factors involved may be related...
Age and vocal cord carcinoma
As the population ages, the management of vocal fold carcinomas should be evaluated. In this retrospective study on 33 patients aged 75 and more, the authors compared the results of radiotherapy and endoscopic treatment for T1 and T2 glottic carcinoma....
Not as rare as we think? Silent sinus syndrome incidence on CT heads
It is relatively uncommon to come across a case of silent sinus syndrome (SSS), but not as rare as the prevalence in the literature might suggest – the authors of this study note that only 100 cases are reported in...
Hearing outcomes after mastoid obliteration tympanoplasty
In this study, the authors retrospectively compare hearing outcomes after mastoid obliteration to non-obliterative techniques in cholesteatoma surgery. They have performed canal wall up with mastoid obliteration (bony obliteration tympanoplasty or BOT) since 2013. The procedure has replaced canal wall...
Epithelial risk factors
This review paper from Barcelona retrospectively assesses patients diagnosed with oral epithelial dysplasia between 1995-2014 and followed up until 2017. In total, 144 cases were noted, of which 42% progressed to an oral cancer by the time of review in...
Factors influencing transformation of laryngeal dysplasia to malignancy in a 10-year review
Laryngeal dysplasia has a propensity to change into malignancy, the generally reported rate of this being about 14%. In this retrospective study of 125 patients, the authors have assessed the severity of dysplasia in relation to the incidence and time...
