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The hidden dementia in motor neurone disease

It is now well recognised that people with motor neurone disease (also known as amyotrophic lateral sclerosis) are at risk of developing frontotemporal dementia. It can be difficult to recognise the symptoms of cognitive decline in this group due to...

The septum and breathing

The authors compared the improvement in nasal obstructive symptoms in two groups of patients. One group underwent septoplasty alone and the other septoplasty accompanied with compensatory turbinoplasty. They used the Nasal Obstruction Symptom Evaluation (NOSE) [12] and visual analog scale...

Salivary pepsin – a simple test for LPR?

A diagnosis of laryngopharyngeal reflux (LPR) can be made on the basis of characteristic symptoms and nasendoscopy findings. Objective tests exist for this condition; for example, 24-hour dual-channel pH-metry which is considered to be the gold standard. Such tests are,...

Globus – benign when the sole symptom

This is a prospective cohort study of Danish patients that presented to an otolaryngologist’s office with globus over the course of a year. They accounted for 4% of new patients, amounting to 122 patients in this study (57 patients were...

A new treatment for chronic rhinitis

The review paper looks at the efficacy of cryoablation of the posterior nasal nerve (PNN) to treat chronic rhinitis, an increasingly popular method of treating a highly prevalent and morbidity-inducing disease. Five studies were included in the meta-analysis, all dating...

Do nasal septal deviation and septoplasy affect Eustachian tube function?

The authors suggest that nasal septal deviation (NSD) or septoplasty possibly affect Eustachian tube (ET) function. They conclude this from their prospective study on 25 patients who underwent septoplasty for NSD. These patients aged above 14 years had no other...

A lateralised middle turbinate post pituitary surgery and incidence of sinusitis

A common belief amongst pituitary surgeons is that lateralising the middle turbinate to access the sphenoid can result in an iatrogenic sinusitis. This paper attempts to find out whether this is in fact true. Thirty-eight patients fitted the inclusion criteria...

Long-term results for dupilumab are very promising!

Eosinophilic chronic rhinosinusitis (eCRS) is complicated by frequent early and aggressive recurrence of polyps after both medical and surgical treatment regimes. Dupilumab is an anti-IL-4/IL-3 receptor monoclonal antibody and has been previously studied in the SINUS-52 study, with an observation...

Is GERD linked to CRS?

We are all well aware that both chronic rhinosinusitis and reflux are prevalent in our populations. This meta-analysis looked at 25 studies investigating the association between GERD, LPR and CRS, therefore evaluating more than 117,000 patients. The results are fascinating...

Lockdown has been bad for children, but it might mean they don’t need surgery anymore

Our editor’s choice for this edition reviews an article looking at the effects of lockdown on symptom prevalence in children with adenotonsillar diseases. In this unprecedented COVID-19 era that we are all living and working in, risk assessment has taken...

Does Eustachian tube dysfunction improve with FESS?

This multinational study prospectively collected SNOT-22 data to determine the prevalence and severity of, and whether endoscopic sinus surgery (ESS) had improved, symptoms of Eustachian tube dysfunction in patient with chronic rhinosinusitis (CRS). The SNOT-22 includes two questions which are...

Prevention better than cure?

This systematic review looks at methods of ‘barrier protection’ or ‘barrier-enforcing’ to minimise allergic rhinitis symptoms, using 15 RCTs. Whilst the authors admit that patient numbers were small in a number of these studies, generally it seems that barrier techniques...