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Systemic steroid therapy for reduction of macrophage migration inhibition factor in the control of nasal polyposis
It is believed that macrophage migration inhibitory factor mediates inflammation by stimulating the release of other pro-inflammatory cytokines. The use of systemic steroids in control of nasal polyposis is an established treatment. In this study the authors have aimed at...Neurological idiopathic disease: a shared journey for NASA and medicine
Whilst Southampton can’t really be described as an extreme environment, experiments carried out in the city have certainly been taken out of this world. Robert Marchbanks discusses one of the associations between Southampton, The International Space Station and tympanic membrane...
Adjuvant intratympanic steroid therapy in sudden sensorineural hearing loss
Sudden sensorineural hearing loss (SNHL) means abrupt hearing loss by 30dB affecting three consecutive frequencies within 72 hours. This is treated by high tapering doses of systemic steroids, the role of which is controversial and fraught with possible complications in...Dysphagia in complex laryngology – maintaining the balance
These authors from the speech and language therapy department at Imperial College Healthcare NHS Trust, describe their view of a patient-centred approach to managing dysphagia in complex laryngology. Careful consideration of the balance of airway, voice and swallow, which is...Endoscopic ‘syringe and cutdown’ technique for nasolacrimal duct obstruction in children
This article presents a novel yet simple technique to help in the management of congenital NLDO. The authors propose it as a valuable addition to existing standard procedures. Congenital nasolacrimal duct obstruction (NLDO) is a condition encountered within the first...Malignant lesions and reconstruction of the pinna
External ear reconstruction can be challenging. Baskaran Ranganathan and Amr Abdelhamid describe how careful assessment, planning and surgery following the subunit principles and reconstructive ladder will ultimately lead to good aesthetic outcomes with restored form and function. The external ear,...Anaesthesia for excision of vestibular schwannomas
The ‘shared airway’ relationship between ENT surgeons and anaesthetists is well documented. But ENT surgery and anaesthesia interact in numerous other ways, particularly in complex skull base surgery. What do our anaesthetic colleagues want us to know about vestibular schwannoma...Impact of outer ear problems in Northern Ethiopia: experiences of a global outreach clinic
Outer ear disease is one of the commonest reasons for attending the ENT clinic in Ethiopia, just as in the UK. Very little has been published on the experiences of ENT clinics in Ethiopia. Here Yilkal Tassew, Seid Temam and...
Maintaining a voice throughout the MND journey
Amytrophic lateral sclerosis, also known as motor neurone disease (MND), is a progressive neurological disease that destroys the nerve cells responsible for controlling voluntary muscle movements resulting in severe dysarthria in 95% of people with MND. It may lead to...
Intratympanic steroids - to give or not to give?
The treatment of idiopathic sudden sensorineural hearing loss (ISSNHL) is controversial and different modes of steroids have been tried without any universal consensus. Various authors have reported combined oral and intratympanic steroid therapy in SSNHL, with consistent results in several...
The hidden dementia in motor neurone disease
It is now well recognised that people with motor neurone disease (also known as amyotrophic lateral sclerosis) are at risk of developing frontotemporal dementia. It can be difficult to recognise the symptoms of cognitive decline in this group due to...
