You searched for "molecular"

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In conversation with Prof Helge Rask-Andersen: on cell regeneration and treatment of human deafness

Helge Rask-Andersen, head of the inner ear research laboratory at the University of Uppsala in Sweden, has many achievements to his name. He was made an Honorary Member of ENT UK earlier this year. Gerry O’Donoghue caught up with him...

In conversation with Prof Helge Rask-Andersen: on cell regeneration and treatment of human deafness

Helge Rask-Andersen, head of the inner ear research laboratory at the University of Uppsala in Sweden, has many achievements to his name. He was made an Honorary Member of ENT UK earlier this year. Gerry O’Donoghue caught up with him...

Chronic rhinosinusitis – a pre-malignant condition?

Nasopharyngeal carcinoma (NPC) is a relatively uncommon diagnosis in the West but is prevalent in Southeast Asia. Several factors have been established to be associated with a higher risk of developing NPC, including salted fish consumption, smoking, alcohol, and Epstein...

The integration of targeted therapy and surgery in advanced thyroid cancer clinical trials

One of the headline speakers, Mark Zafereo, will be talking at IFOS about thyroid cancer. We hear from his team about some of the areas they will be discussing. Locally advanced thyroid cancer generally refers to patients who have significant...

Hearing loss and Alport syndrome

Alport syndrome (AS) includes a group of hereditary diseases caused by mutations in the COL4A3, COL4A4 or COL4A5 genes. These genes are responsible for the biosynthesis of α3, α4 and α5 collagen IV chains, which are located in the glomerular...

Hearing about genes

I have been fortunate in my career to travel as an invited lecturer at many hospitals, universities and professional societies around the world. I have spoken to audiology societies, otolaryngology societies, and university communication disorders programmes in Europe, Asia, Africa,...

Genetic research on hereditary hearing loss and clinical application in the Chinese population

Congenital deafness in China affects more people than the entire population of Australia. Prof Wang give us a comprehensive insight into one of the main congenital disabilities in China, looking into the causes of deafness and the benefits of genetic...

Thyroid nodules in children

Whilst 5% of nodules in adults may harbour malignancy it is reported in this review that about a quarter of nodules may do so in children. Malignancies in this group are almost always well-differentiated subtypes of papillary, follicular and medullary...

Thyroid cancer: to dissect the neck or not?

This is a good review of the much-debated management of the neck in thyroid cancer. It discusses oncological goals that must be achieved whilst maintaining voice, swallowing and parathyroid function. A clear description is made of the common nodal basins...

In space no-one can hear you scream…or can they?

Plasma, eardrums the size of planets and questioning the wisdom of your school physics teacher! Martin Archer explains the fascinating world of sound and space. Is there sound in space? If you believed the marketing of the movie Alien, or...

Focus on ENT trainees with additional qualifications

In this Trainee Matters, we focus on ENT trainees with additional qualifications. Eight accomplished trainees tell Emma Stapleton how their achievements have benefitted them both professionally and personally. Their professional achievements have included a National Training Number in ENT, presentations,...

Physiological mechanisms of hyperacusis: an update

Hyperacusis is a heterogeneous and complex clinical entity, and proposals about physiological mechanisms should reflect these issues. Ben Auerbach helps us navigate through present knowledge in this area, and proposes future directions for research. Hyperacusis is a debilitating hearing disorder...