You searched for "trial"
Prevention better than cure?
This systematic review looks at methods of ‘barrier protection’ or ‘barrier-enforcing’ to minimise allergic rhinitis symptoms, using 15 RCTs. Whilst the authors admit that patient numbers were small in a number of these studies, generally it seems that barrier techniques...How to safely image patients with cochlear implants
Cochlear implants have quickly become a widely used aid for hearing-impaired people. As these implants include metal elements, the choice of an appropriate imaging modality for patients carrying such devices should receive special attention. This is important due to image...
Multiple free flaps for head and neck cancer
Most patients with advanced head and neck cancers now undergo microvascular free flap reconstruction. This is mainly as flaps facilitate complete tumour and margin removal by providing reliable wound coverage and better restoration of form and function. However despite this,...
Serum biomarkers for CRSwNP
This cross-sectional comparative study looked at 50 patients with nasal polyps who, at the time of diagnosis, also had a blood test evaluating serum total IgE, IL-17 and Pentraxin-3. The study assesses whether these blood markers are useful in the...
Audiometric outcomes following endoscopic stapes surgery
Adding to the evidence base for endoscopic stapes surgery, this systematic review and analysis of outcomes sought to establish the efficacy and safety of this approach. This review included 14 studies with a pooled sample of 314 adult patients. The...
Surgical management of refractory osteoradionecrosis
This is a French single-centre, 10-year experience of 55 surgical resection and reconstruction procedures. They claim an overall effectiveness rate of 92.3%. A total of 36 segmental and 19 marginal mandibulectomies were performed. A variety of free flaps were used,...
More than words: looking at all the evidence
Evidence based practice (EBP) is a three-pillared approach whereby information on the research evidence, factors relating to the patient and clinical experience are all considered to inform a care decision. Unfortunately, there is frequently very little research evidence to inform...
A novel way to reduce postoperative nausea and vomiting
This is an interesting RCT which evaluates the prophylactic effect of bilateral endoscopic injection of local anaesthetic in the sphenopalatine ganglion (SPG) on postoperative nausea and vomiting (PONV). It has a robust design, and is sufficiently powered and blinded, with...
Management of stage IV pharyngolaryngeal lesions
This is a retrospective study of 63 patients presenting with stage four laryngeal and/or hypopharyngeal squamous cell carcinoma. The aim was to define the factors influencing the oncological and functional outcomes of the patients. All patients had T4 lesions with...
Does trainee participation in cochlear implant surgery affect operative times?
The role of surgical education is a very sensitive issue in spite of the obvious need and the obligation of doctors to pass on their knowledge and experience to the next generation. This study is very interesting as it assesses...
Submental island flap to reconstruct the lower lip
The lips are necessary for oral competence, cosmesis, speech and feeding. Non-melanoma cancers can affect the lips, and the lower lips are about 80% more likely to be affected. A large number of these cancers are squamous cell carcinomas. Treatment...
