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943 results found

Steroid use in acute acoustic trauma

Acute acoustic trauma (AAT) injuries include noise-induced damage to inner and middle ear presenting as hearing loss, tinnitus and vertigo. Classic presentation is sensorineural hearing loss with an intact tympanic membrane. The authors carried out a case-control study in military...

Lost and sound: exploring hyperbaric oxygen therapy for refractory SSNHL

Can hyperbaric oxygen therapy (HBOT) offer a breakthrough for patients with refractory sudden sensorineural hearing loss (SSNHL)? SSNHL is defined as acute hearing loss of ≥30 decibels in three consecutive frequencies within three days. Typically, it’s treated with two weeks...

Patients with severe uncontrolled CRSwNP respond to biologics in the real world

Clinical trials have demonstrated that biologics are effective in treating patients with chronic rhinosinusitis with nasal polyps (CRSwNP). This multicentre (15 tertiary care centres in France) observational prospective cohort study aims to examine the effectiveness of biologics in treating CRSwNP...

EBM Stats Calc: there’s a stat for that

Quantifying the value of a specific test or intervention for a patient is no easy feat. Even when the value of a given test or intervention has been established, there may be additional case-specific factors to consider that are not...

Cyclops Medtech partners with Hypatia Specialist Clinics

Cyclops Medtech is partnering with Hypatia Specialist Clinics to provide vestibular diagnostic and therapeutic solutions throughout the United Kingdom and parts of Europe.

Neuromod publishes results of second large-scale clinical trial for tinnitus, shows greater improvement of symptoms

Neuromod Devices, the medical device company specialising in tinnitus, has published the results of its TENT-A2 (Treatment Evaluation of Neuromodulation for Tinnitus – Stage A2) clinical trial in the scientific journal, Nature – Scientific Reports in a paper titled ‘Different bimodal neuromodulation settings reduce tinnitus symptoms in a large randomized trial’.

Recruitment of Sudden Hearing Loss Patients for Clinical Trial: Novel Compound AC102 Outperforms Corticosteroids Preclinically

While corticosteroids are widely used to treat Sudden Sensorineural Hearing Loss (SSNHL), there is still no therapy with proven efficacy and regulatory approval for this debilitating condition.

Neuromod advances multiple regulatory approvals to expedite Lenire’s global availability

Neuromod, the medical technology company that created the Lenire® tinnitus treatment device, has announced approval to the Medical Device Single Audit Program (MDSAP) and EU Medical Device Regulation (MDR) certification. Neuromod’s MDSAP certification follows a comprehensive audit verifying compliance with...

Role of interventional neuroradiology in otorhinolarygological pathology 
– a brief review

Introduction Since its advent in 1964 when Dotter percutaneously dilated a stenosed femoral artery [1], interventional radiology has undergone tremendous advancement in both imaging and devices that have enabled the operator (interventional radiologist) to access very distal small vasculature and...

Where is that sound? Not every hot tub is a jacuzzi

Evidence suggests that the incidence of sound sensitivity and general noise intolerance is increasing. Studies have suggested that the incidence of hyperacusis is between 8% and 15.2% of the adult population. There is a correlation between the prevalence of hyperacusis...

Bevacizumab, NF2, hearing and age

Introduction NF2-related schwannomatosis (NF2-SWN) is an autosomal dominant disorder leading to the development of schwannomas, meningiomas and spinal cord ependymomas. Younger age is a negative prognostic factor. Treatment includes observation, surgery, radiotherapy and medical therapy with bevacizumab (VEGF monoclonal antibody)....

New treatment for chronic voice disorders

A new regenerative treatment for people with chronic voice disorders has been used in the UK for the first time. Guy’s and St Thomas’ is the first NHS trust in the country to provide this treatment in the larynx (or voice box) for patients with chronic voice conditions that cause voice change or dysphonia, making the voice sound hoarse, strained, breathy, weak, or fluctuate in pitch and loudness.