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Genetics WG4. Improving diagnosis and drug development through the genetic understanding of tinnitus subtypes: a TINNET endeavour

Christopher R Cederroth and Jose Antonio Lopez-Escamez explain how progress is being made to investigate the contribution of genetic factors to tinnitus, including a subtype of ‘extreme’ tinnitus in Ménière’s disease. Genetics WG4 is working towards determining the genetic basis...

Intermediate risk factors SCC tongue

This retrospective review from Japan assessed 89 patients who underwent surgery for squamous cell carcinoma of the tongue, specifically they reviewed the evidence of perineural and vascular invasion (27.0% and 23.6%). Their results suggest, not unsurprisingly, that perineural and vascular...

No difference upper or lower lip

This is a retrospective review from the Netherlands over a 20-year period to 2009 of squamous cell carcinoma (SCC) of the lip. In total, 979 cases of the lower lip were identified and 126 of the upper lip, with men...

Reasons for rejection of BAHA in patients with unilateral hearing loss

Ever since Tjellström first developed the procedure of BAHA implantation, the techniques have come a long way towards faster and more convenient surgical methods to offer better hearing for a wide variety of conditions. Unilateral hearing loss has now been...

Amount of dietary iodine and thyroid cancer

Two molecular scientists from Zurich wrote this paper as a systematic review, asking the question of whether dietary iodine intake is a risk factor for developing thyroid cancer later on life. They speculate that low iodine intake is a risk...

Serum urea and epistaxis

This was a small retrospective review from Swansea looking at 278 patients who attended a teaching hospital Accident and Emergency department with a diagnosis of epistaxis. Only 119 of these patients had their serum urea measured. The investigators found that...

Hearing preservation after Gamma knife in vestibular schwannomas

This retrospective study reports the outcomes of hearing preservation up to three years after Gamma knife radiosurgery for Gardner-Robertson Class I (SDS>70% and PTA <30dB) patients with vestibular schwannomas. The authors report that patients with no subjective or objective hearing...

The association of frontal recess anatomy and mucosal disease on the presence of chronic frontal sinusitis: a computed tomographic analysis

Ostial obstruction is a primary pathophysiological mechanism contributing to sinusitis, which can be caused by anatomical variations, mucosal inflammation or both. This retrospective case series aimed to identify anatomical factors and inflammatory areas relating to chronic frontal sinusitis on nasal...

Sulcus vocalis in patients attending voice clinics: A retrospective study

Sulcus vocalis was first described by Giacomini. This includes a variety of anatomic indentations of the vocal fold, ranging from shallow longitudinal furrows to deep vocal cord pits. This retrospective study was conducted at King Saud University between 2006 and...

Cochlear implantation in Ménière’s disease

This was a Belgian retrospective study of seven patients with Ménière’s disease who underwent cochlear implantation. All patients had bilateral severe to profound hearing loss and all met AAO-HNS criteria for Ménière’s disease. Follow-up for patients ranged from six months...

Long-term outcomes after endoscopic pituitary macroadenomas resection

In this retrospective study the authors attempted to find out long-term outcomes after pituitary macroadenoma resection via the endonasal endoscopic transsphenoidal route. Eighty of the 162 patients operated on met the study criteria of clinical and radiological follow-up for at...

Cochlear implants in Ménière’s disease

This retrospective review firstly reminds us that a cochlear implant (CI) is possible with Ménière’s disease (MD) and provides a good account of what can be expected with a CI in patients with MD. Twenty MD patients who underwent cochlear...