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Systemic steroid therapy for reduction of macrophage migration inhibition factor in the control of nasal polyposis

It is believed that macrophage migration inhibitory factor mediates inflammation by stimulating the release of other pro-inflammatory cytokines. The use of systemic steroids in control of nasal polyposis is an established treatment. In this study the authors have aimed at...

Medication and its effect on the larynx

This article summarises different medications and their effect on the voice. A growing number of patients we see in clinic are on multiple medications that could affect vocal cord function. The author summarises different classes of medications and their potential...

Eosinophilic or not eosinophilic: dupilumab seems to work

Chronic rhinosinusitis with nasal polyps (CRSwNP) is a type 2 inflammation with interleukin (IL)-4, IL-13, and IL-5. Tissue eosinophilia in nasal polyps dramatically increased over a 10-20-year period. Classification of the severity of eosinophil status is expected to lead to...

Are cardiovascular risk factors associated with hearing loss?

Cardiovascular disease (CVD) risk factors are associated with microvascular damage that can impair molecular transport across capillary walls and cause inflammation and oxidative stress that may damage cochlear structure and function. This study determined, among a population-based sample of Canadian...

A comparison between biologic and surgical treatment (FESS) for chronic rhinosinusitis with polyposis

In recent years, it is being increasingly recognised that chronic rhinosinusitis with nasal polyps (CRSwP) is a type 2 chronic inflammation based on IL-4 and IL-13, and the novel monoclonal antibody, such as dupilumab, is likely to have a major...

Factor favouring the need for revision FESS in chronic sinusitis with polyps – a multivariate analysis including phenotypes

Chronic rhinosinusitis with polyposis is a type 2 inflammation with risks of recurrence and need for revision operations. This is known to depend on the endotype and phenotype factors. This is a retrospective study of 212 patients. Of these, 112...

Clinical WG1. Establishing a standard for tinnitus: patient assessment and characterisation

Rilana Cima and Haúla Haider introduce an ambitious pan-European collaboration that seeks to establish guidelines for achieving best clinical practice for managing, assessing and treating patients with different tinnitus profiles. Tinnitus heterogeneity is the major reason for inconsistent results in...

Effects of blast and acoustic trauma: assessment of hearing status on war veterans

Introduction Acoustical conditions of the military are often dangerous and there is a real risk of blast trauma and acoustic trauma [1, 2]. Levels of military noises maybe reach up to 125 dBA [3]. Weapons produce instant shock waves (10μs)...

Imaging and management of head and neck vascular anomalies

Vascular anomalies are a diffuse spectrum of abnormalities which often involve the head, neck and oral cavity. They are frequently misnamed, often being generically labelled as haemangiomas. This lack of basic understanding can cause confusion leading to a cascade of...

Dysphagia

Natalie Watson, MBBS, MA, FRCS (ORL-HNS), Consultant ENT Surgeon Specialising in Laryngology, Guy’s and St Thomas’ NHS Foundation Trust, UK. nataliewatsonent@gmail.com@surgeonsinger Guest Section Editor The function of swallowing is one third of the triad of laryngology. Dysphagia describes difficulty swallowing...

Imaging tinnitus

Tinnitus is a common sensation with a reported prevalence of 7-32%. The British National Study of Hearing recorded that 10% of adults suffered from prolong spontaneous tinnitus, and approximately a quarter of these are subsequently referred to hospital for investigation...

Livio™ AI: In Conversation with Achin Bhowmik

A hearing aid? A Fitbit? A falls alert device? A ‘Healthable’? Achin Bhowmik discusses how Starkey’s Livio AI came to market and what it means for the future of amplification devices. Achin Bhowmik. Achin, you have an interesting background in...