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A place for everything and everything in its place: the practicalities of randomised clinical trials
Will this pill cure tinnitus? Bonnie Millar describes one trial that has investigated the possibility whilst describing the path of drug trials in the UK. Background In the last quarter of 2014, a clinical trial (QUIET-1; ClinicalTrials.gov Identifier: NCT02315508) commenced...
Which factors affect the postoperative CSF leak following endoscopic skull base surgery?
Endoscopic skull base surgery is being increasingly performed worldwide for skull base tumours. Common indications include pituitary tumours, rathke cleft cysts, chordomas, craniopharyngiomas and olfactory neuroblastomas. The most common and important complication following endoscopic skull base surgery is postoperative CSF...
Can a serpent-shaped graft enhance your nose?
The success of rhinoplasty is highly variable and the technique employed by the operating surgeon must be tailored for different patient demographics. This group from China describes the structural differences in nasal configuration within the Asian population, notably an under-projected...Selective upper airway stimulation
Obstructive sleep apnoea (OSA) is one of the most common diseases in industrialised countries and is characterised by an intermittent obstruction of the upper airway during sleep. The standard treatment for OSA is continuous positive airway pressure (CPAP) therapy, which...
Person-centred care, enhancing audiology student understanding across the globe
Over 200 students registered for a multinational virtual event facilitated by the Ida Institute. The aim was to determine levels of student understanding and approaches to person-centred care (PCC), alongside the opportunity to evaluate the benefits of this approach to...The HEARO Procedure for cochlear implantation
Cochlear implants have become the state-of-the-art treatment for profound to severe sensorineural hearing loss. Since its popularisation, many aspects of this technology have constantly been optimised. Processors have become smaller, are worn behind the ear and are even water resistant....
Reconstruction of the Head and Neck: A Defect-Oriented Approach
This is the second Thieme book on head and neck cancer by this author that follows on from Head and Neck Cancer: an Evidence-Based Team Approach four years ago. It is a well-structured, up-to-date book in a readable layout with...Congenital cytomegalovirus causing deafness in children: an update
Congenital CMV is the leading non-genetic cause of sensorineural hearing loss in children. Keith Trimble draws our attention to this and gives a comprehensive guide on diagnosis and treatment. Congenital cytomegalovirus (cCMV) infection is common, affecting 1% of all newborns,...
OTO-104 in noise-induced and cisplatin-induced hearing loss
These two animal studies report on potential new applications for intra-tympanic OTO-104, a slow-release hydrogel formulation of dexamethasone that is currently being used in a Europe-wide randomised trial for Ménière’s disease. In the first paper, guinea pigs were given a...Endoscopic airway interventions in children
Open surgery for paediatric airway pathologies such as subglottic stenosis was hailed as revolutionary when many of today’s paediatric ORL specialists were in training. Equipment, facilities and training has moved on and the high-quality optics in modern endoscopes, coupled with...SCOTLAND preoperative tympanomastoid CT temporal bone mnemonic system
Learning how to interpret a CT scan of the temporal bones can be a daunting task, especially for a head and neck surgeon like me! However, to make life easier, the authors have devised a useful system to help cover...
