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2081 results found

Follicle stimulating hormone receptors; an aid for the pathologist?

It is well known that Follicle Stimulating Hormone receptors (FSHRs) are found in extra-gonadal tumours such as those within thyroid tissue. This Polish study analysed 44 thyroid resection specimens to look for the presence of these receptors. No mention is...

Patient-reported outcome measures in septorhinoplasty

Patient-reported outcome measures (PROMs) are used increasingly in surgical research to quantify the efficacy of surgical interventions. This can help to fill an ‘evidence gap’ where healthcare rationing threatens particular treatments. Procedures aimed at improving quality of life, especially with...

Alcohol and the vestibulo-ocular reflex (VOR)

I was drawn to this paper initially for slightly unscientific reasons but in fact it proved a worthwhile read. It describes the effect of alcohol consumption on the VOR of eight healthy subjects as measured using video head impulse testing...

Visual vertigo and optokinetic response

This study measured differences in optokinetic responses (sitting, standing, with and without a static visual target) in three groups of people: those classified as having unilateral vestibular loss (n=10), unilateral loss with visual vertigo (n=8) and a control group (n=10)....

Nasal decongestants don’t improve Eustachian tube function

Prescribing nasal steroids and decongestants. It’s something most of us do routinely, in an effort to reduce chronic middle ear effusion in an adult by trying to improve eustachian tube (ET) patency. This study used clever devices (tube manometry and...

Earplugs fit for purpose

The aim of occupational audiology is to prevent hearing loss caused by occupational sound exposure which can exacerbate the long-term effects of central presbyacusis as employees age. To provide the best noise protection over time, research suggests that best practice...

Dysphagia services in the emergency department

The emergency department acts as the first port of call for many individuals with wide-ranging diagnoses and conditions, several of whom may potentially present with dysphagia. It is not a usual environment in which speech and language therapists regularly work,...

Genetics of IP-III

The authors provide a literature review of the genetic basis and clinical features of incomplete partition (IP)-type III. The condition is seen typically in males and is due to mutation in the POU class 3 homeobox 4 (POU3F4) gene which...

A useful adjuvant treatment for SNAC or IP

5-Fluorouracil (5FU) is a topical preparation used in the treatment of various dermatological, ocular and gynaecologic malignant and pre-malignant conditions, and this literature review looks at the efficacy of 5FU in treating inverted papilloma and sinonasal tumours. The authors cite...

Demonstrating unobservable effects of therapy through PROMS: a review

Ultimately, healthcare should meet the needs of the people it is designed for. One way of measuring this is using patient-reported outcome measures (PROMS). These tools capture the patient’s perspective and have been described as demonstrating the unobservable effects of...

Earplug use in clubbers

Past studies show that there is a low frequency of use of earplugs at music events. In this research article produced by the National Acoustic Laboratories, Australia, a group of 51 regular attendees at music events were recruited and given...

Treatment of olfactory dysfunction

The sense of smell is crucial to our being able to relish food and experience our environment. Olfactory dysfunction has been trivialised or ignored previously, but the negative consequences of the loss of sense of smell are being increasingly highlighted....