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SEQaBOO: SEQuencing a Baby for an Optimal Outcome
There are at least 15 countries now running genome sequencing projects. The team in Manchester, UK, and Boston, USA, share their SEQaBOO project. Abstract SEQaBOO (SEQuencing a Baby for an Optimal Outcome) will transform newborn hearing screening (NBHS) by bringing...
Early injection laryngoplasty for iatrogenic vocal fold movement impairment – a safe and effective treatment
This Ed’s Choice examines the role of early injection laryngoplasty on swallowing dysfunction and is one of a few studies available in the literature. Research on early injection laryngoplasty has been predominately focused on voice and reducing the risk of...Hearing in middle-age: hearing impairment, tinnitus and hearing aid use in UK adults
Hearing loss has a well-documented adverse impact on emotional, social and physical well-being. In this article, Dr Piers Dawes from the University of Manchester gives an insight into his team’s recent work analysing the very large UK Biobank data set,...In conversation with Professor Graeme Clark
As we celebrate the cochlear implant, we celebrate an amazing work of innovative biomedical engineering that is a life-changer to many recipients around the world. We take for granted the arduous journey of the cochlear implant since its conception. Eric...
Thyroidectomy patient survey regarding voice outcomes
One of the common adverse effects following thyroid surgery is a change in voice, which may be related to iatrogenic injury to the recurrent laryngeal nerve or superior laryngeal nerve during surgery or by direct cancer involvement. The burden of...
A bittersweet finding
This is an elegant study, documenting the role of, and activation of, nitrous oxide in chronic sinusitis. Bitter taste receptors (TR2) have recently been identified as novel ‘players’ in sinonasal innate immunity and in chronic rhinosinusitis. The receptors are triggered...
What we need to know about the new frontier of inner ear therapies
This is an interesting and topical review of the emerging biotechnology and pharmaceutical solutions for hearing loss and related conditions such as tinnitus. This paper suggests we are on the cusp of a very large step-change in the way we...
Prognostic value of neutrophil-to-lymphocyte ratio in HPV-positive oropharyngeal cancer
The authors propose that high neutrophil-to-lymphocyte ratio (NLR) is associated with poor disease-free survival (DFS) in patients with human papillomavirus positive (HPV+) oropharyngeal cancer (OPC). This is a retrospective study that compared the outcomes of 43 patients treated for HPV+...Job Ahead: understanding the business and financial aspects of US practice
Dr Christiansen brings over 30 years of experience as a practising otolaryngologist both in private practice and in academic medicine as Associate Professor of Clinical Otolaryngology at the University of Missouri School of Medicine. Dr Christiansen started his career in...
Wearable tech revolutionising sleep monitoring: a new era in sleep health
Restful sleep is crucial for health but conditions like obstructive sleep apnoea (OSA) can significantly disrupt it, leading to fatigue, cardiovascular issues, and other serious health problems. Polysomnography (PSG) remains the gold standard for OSA diagnosis [1], however it is...
The increasingly favourable outcomes from endoscopic endonasal approaches for the management of pituitary adenomas
Historically, pituitary tumours have been surgically managed with an open, transcranial approach. Although this approach still has its merits in large intracranial adenomas, technological advancement has allowed smaller tumours to be debulked via a transseptal microscopic technique. These days, the...
